Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience

Introduction. Granulocyte colony-stimulating factor (G-CSF) therapy is commonly used in kidney and liver transplant recipients with severe neutropenia. However, rapid and high increases in neutrophil counts of some patients may occur during treatment. This retrospective study aimed to determine the...

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Main Authors: Emel Isiktas Sayilar, Alparslan Ersoy, Sedat Çelikçi, Vildan Ozkocaman, Fahir Özkalemkaş, Rıdvan Ali, Yavuz Ayar
Format: Article
Language:English
Published: Nizameddin KOCA 2020-01-01
Series:Turkish Journal of Internal Medicine
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/944535
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author Emel Isiktas Sayilar
Alparslan Ersoy
Sedat Çelikçi
Vildan Ozkocaman
Fahir Özkalemkaş
Rıdvan Ali
Yavuz Ayar
author_facet Emel Isiktas Sayilar
Alparslan Ersoy
Sedat Çelikçi
Vildan Ozkocaman
Fahir Özkalemkaş
Rıdvan Ali
Yavuz Ayar
author_sort Emel Isiktas Sayilar
collection DOAJ
description Introduction. Granulocyte colony-stimulating factor (G-CSF) therapy is commonly used in kidney and liver transplant recipients with severe neutropenia. However, rapid and high increases in neutrophil counts of some patients may occur during treatment. This retrospective study aimed to determine the efficacy and safety of G-CSF treatment in neutropenic kidney transplant recipients. Methods. Eight kidney transplant recipients treated with G-CSF for drug-induced neutropenia (neutrophil count
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spelling doaj.art-2c72a5ff53a749eab71154cb437bc9fc2023-02-15T16:10:34ZengNizameddin KOCATurkish Journal of Internal Medicine2687-42452020-01-0121111810.46310/tjim.6550911881Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experienceEmel Isiktas Sayilar0Alparslan Ersoy1Sedat Çelikçi2Vildan Ozkocaman3Fahir Özkalemkaş4Rıdvan Ali5Yavuz Ayar6UFUK ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, NEFROLOJİ BİLİM DALIULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, NEFROLOJİ BİLİM DALIULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALIULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALIULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALIULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, İÇ HASTALIKLARI ANABİLİM DALI, HEMATOLOJİ BİLİM DALIBURSA ŞEHİR HASTANESİ, NEFROLOJİ KLİNİĞİIntroduction. Granulocyte colony-stimulating factor (G-CSF) therapy is commonly used in kidney and liver transplant recipients with severe neutropenia. However, rapid and high increases in neutrophil counts of some patients may occur during treatment. This retrospective study aimed to determine the efficacy and safety of G-CSF treatment in neutropenic kidney transplant recipients. Methods. Eight kidney transplant recipients treated with G-CSF for drug-induced neutropenia (neutrophil counthttps://dergipark.org.tr/tr/download/article-file/944535filgrastimgranulocyte colony-stimulating factorkidney transplantationleukopenianeutropenia
spellingShingle Emel Isiktas Sayilar
Alparslan Ersoy
Sedat Çelikçi
Vildan Ozkocaman
Fahir Özkalemkaş
Rıdvan Ali
Yavuz Ayar
Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience
Turkish Journal of Internal Medicine
filgrastim
granulocyte colony-stimulating factor
kidney transplantation
leukopenia
neutropenia
title Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience
title_full Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience
title_fullStr Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience
title_full_unstemmed Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience
title_short Granulocyte colony-stimulating factor usage in drug-induced neutropenia after kidney transplantation: a single-center experience
title_sort granulocyte colony stimulating factor usage in drug induced neutropenia after kidney transplantation a single center experience
topic filgrastim
granulocyte colony-stimulating factor
kidney transplantation
leukopenia
neutropenia
url https://dergipark.org.tr/tr/download/article-file/944535
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AT sedatcelikci granulocytecolonystimulatingfactorusageindruginducedneutropeniaafterkidneytransplantationasinglecenterexperience
AT vildanozkocaman granulocytecolonystimulatingfactorusageindruginducedneutropeniaafterkidneytransplantationasinglecenterexperience
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AT rıdvanali granulocytecolonystimulatingfactorusageindruginducedneutropeniaafterkidneytransplantationasinglecenterexperience
AT yavuzayar granulocytecolonystimulatingfactorusageindruginducedneutropeniaafterkidneytransplantationasinglecenterexperience