The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries
Sheng-En Chou,1 Cheng-Shyuan Rau,2 Wei-Ti Su,1 Ching-Hua Tsai,1 Shiun-Yuan Hsu,1 Ching-Hua Hsieh1 1Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospita...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2023-02-01
|
| Series: | Risk Management and Healthcare Policy |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-association-of-albumin-bilirubin-albi-grade-with-mortality-risk-in-peer-reviewed-fulltext-article-RMHP |
| _version_ | 1797894446110474240 |
|---|---|
| author | Chou SE Rau CS Su WT Tsai CH Hsu SY Hsieh CH |
| author_facet | Chou SE Rau CS Su WT Tsai CH Hsu SY Hsieh CH |
| author_sort | Chou SE |
| collection | DOAJ |
| description | Sheng-En Chou,1 Cheng-Shyuan Rau,2 Wei-Ti Su,1 Ching-Hua Tsai,1 Shiun-Yuan Hsu,1 Ching-Hua Hsieh1 1Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, TaiwanCorrespondence: Ching-Hua Hsieh, Tel +886-7-7327476, Email m93chinghua@gmail.comIntroduction: The albumin-bilirubin (ALBI) grade objectively assesses liver function with better performance than the Child-Pugh and end-stage liver disease scores. However, the evidence is lacking on the ALBI grade in trauma cases. This study aimed to identify the association between the ALBI grade and mortality outcomes in trauma patients with liver injury.Methods: Data from 259 patients with traumatic liver injury at a level I trauma center between January 1, 2009, and December 31, 2021 were retrospectively analyzed. Independent risk factors for predicting mortality were identified using multiple logistic regression analysis. Participants were characterized by ALBI score into grade 1 (≤ − 2.60, n = 50), grade 2 (− 2.60 < and ≤ − 1.39, n = 180), and grade 3 (> − 1.39, n = 29).Results: Compared to survival (n = 239), death (n = 20) was associated with a significantly lower ALBI score (2.8± 0.4 vs 3.4± 0.7, p < 0.001). The ALBI score was a significant independent risk factor for mortality (OR, 2.79; 95% CI, 1.27– 8.05; p = 0.038). Compared with grade 1 patients, grade 3 patients had a significantly higher mortality rate (24.1% vs 0.0%, p < 0.001) and a longer hospital stay (37.5 days vs 13.5 days, p < 0.001).Discussion: This study showed that ALBI grade is a significant independent risk factor and an useful clinical tool to discover liver injury patients who are more susceptible to death.Keywords: trauma, liver injury, mortality, albumin-bilirubin grade, ALBI grade, liver function |
| first_indexed | 2024-04-10T07:10:19Z |
| format | Article |
| id | doaj.art-2c7311c440b544d08da4514f18a7b6fb |
| institution | Directory Open Access Journal |
| issn | 1179-1594 |
| language | English |
| last_indexed | 2024-04-10T07:10:19Z |
| publishDate | 2023-02-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Risk Management and Healthcare Policy |
| spelling | doaj.art-2c7311c440b544d08da4514f18a7b6fb2023-02-26T15:41:34ZengDove Medical PressRisk Management and Healthcare Policy1179-15942023-02-01Volume 1627928681871The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver InjuriesChou SERau CSSu WTTsai CHHsu SYHsieh CHSheng-En Chou,1 Cheng-Shyuan Rau,2 Wei-Ti Su,1 Ching-Hua Tsai,1 Shiun-Yuan Hsu,1 Ching-Hua Hsieh1 1Department of Trauma Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, TaiwanCorrespondence: Ching-Hua Hsieh, Tel +886-7-7327476, Email m93chinghua@gmail.comIntroduction: The albumin-bilirubin (ALBI) grade objectively assesses liver function with better performance than the Child-Pugh and end-stage liver disease scores. However, the evidence is lacking on the ALBI grade in trauma cases. This study aimed to identify the association between the ALBI grade and mortality outcomes in trauma patients with liver injury.Methods: Data from 259 patients with traumatic liver injury at a level I trauma center between January 1, 2009, and December 31, 2021 were retrospectively analyzed. Independent risk factors for predicting mortality were identified using multiple logistic regression analysis. Participants were characterized by ALBI score into grade 1 (≤ − 2.60, n = 50), grade 2 (− 2.60 < and ≤ − 1.39, n = 180), and grade 3 (> − 1.39, n = 29).Results: Compared to survival (n = 239), death (n = 20) was associated with a significantly lower ALBI score (2.8± 0.4 vs 3.4± 0.7, p < 0.001). The ALBI score was a significant independent risk factor for mortality (OR, 2.79; 95% CI, 1.27– 8.05; p = 0.038). Compared with grade 1 patients, grade 3 patients had a significantly higher mortality rate (24.1% vs 0.0%, p < 0.001) and a longer hospital stay (37.5 days vs 13.5 days, p < 0.001).Discussion: This study showed that ALBI grade is a significant independent risk factor and an useful clinical tool to discover liver injury patients who are more susceptible to death.Keywords: trauma, liver injury, mortality, albumin-bilirubin grade, ALBI grade, liver functionhttps://www.dovepress.com/the-association-of-albumin-bilirubin-albi-grade-with-mortality-risk-in-peer-reviewed-fulltext-article-RMHPtraumaliver injurymortalityalbumin-bilirubin gradealbi gradeliver function |
| spellingShingle | Chou SE Rau CS Su WT Tsai CH Hsu SY Hsieh CH The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries Risk Management and Healthcare Policy trauma liver injury mortality albumin-bilirubin grade albi grade liver function |
| title | The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries |
| title_full | The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries |
| title_fullStr | The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries |
| title_full_unstemmed | The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries |
| title_short | The Association of Albumin-Bilirubin (ALBI) Grade with Mortality Risk in Trauma Patients with Liver Injuries |
| title_sort | association of albumin bilirubin albi grade with mortality risk in trauma patients with liver injuries |
| topic | trauma liver injury mortality albumin-bilirubin grade albi grade liver function |
| url | https://www.dovepress.com/the-association-of-albumin-bilirubin-albi-grade-with-mortality-risk-in-peer-reviewed-fulltext-article-RMHP |
| work_keys_str_mv | AT chouse theassociationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT raucs theassociationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT suwt theassociationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT tsaich theassociationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT hsusy theassociationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT hsiehch theassociationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT chouse associationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT raucs associationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT suwt associationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT tsaich associationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT hsusy associationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries AT hsiehch associationofalbuminbilirubinalbigradewithmortalityriskintraumapatientswithliverinjuries |