Intestinal GPR119 activation by microbiota-derived metabolites impacts feeding behavior and energy metabolism

Intestinal GPR119 activation by microbiota-derived metabolites impacts feeding behavior and energy metabolism

Objective: The gastrointestinal tract affects physiological activities and behavior by secreting hormones and generating signals through the activation of nutrient sensors. GPR119, a lipid sensor, is indirectly involved in the secretion of incretins, such as glucagon-like peptide-1 and glucose-depen...

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Bibliographic Details
Main Authors: Miki Igarashi, Tetsuhiko Hayakawa, Haruka Tanabe, Keita Watanabe, Akari Nishida, Ikuo Kimura
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Molecular Metabolism
Subjects:
Oleoylethanolamide
GPR119
Satiety
Distal gastrointestinal tract
Gut microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822002186

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