A highly effective ferritin-based divalent nanoparticle vaccine shields Syrian hamsters against lethal Nipah virus

A highly effective ferritin-based divalent nanoparticle vaccine shields Syrian hamsters against lethal Nipah virus

The Nipah virus (NiV), a highly deadly bat-borne paramyxovirus, poses a substantial threat due to recurrent outbreaks in specific regions, causing severe respiratory and neurological diseases with high morbidity. Two distinct strains, NiV-Malaysia (NiV-M) and NiV-Bangladesh (NiV-B), contribute to ou...

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Bibliographic Details
Main Authors: Chunhong Yin, Yan Feng Yao, Peipei Yang, Hang Liu, Ge Gao, Yun Peng, Miaoyu Chen, Mingqing Lu, Xuekai Zhang, Weiwei Guo, Zihan Zhang, Xue Hu, Zhiming Yuan, Chao Shan
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Immunology
Subjects:
Nipah virus
nanoparticle vaccine
attachment glycoproteins (G)
divalent vaccine
immune responses
cross-reactivity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1387811/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1387811/full

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