Interplay of TGFβ signaling and microRNA in thyroid cell loss of differentiation and cancer progression

Interplay of TGFβ signaling and microRNA in thyroid cell loss of differentiation and cancer progression

ABSTRACT Thyroid cancer has been rapidly increasing in prevalence among humans in last 2 decades and is the most prevalent endocrine malignancy. Overall, thyroid-cancer patients have good rates of long-term survival, but a small percentage present poor outcome. Thyroid cancer aggressiveness is essen...

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Bibliographic Details
Main Authors: Cesar Seigi Fuziwara, Kelly Cristina Saito, Edna Teruko Kimura
Format: Article
Language:English
Published: Brazilian Society of Endocrinology and Metabolism
Series:Archives of Endocrinology and Metabolism
Subjects:
Thyroid cancer
microRNA
TGFβ
EMT
thyroid cell differentiation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972019005007108&lng=en&tlng=en

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