Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas
The purpose: to establish influence of a full ischemia of different duration and the subsequent reperfusionon pathology development in pancreas of rats by means of laser speckle-visualization and lifetime digital microscopy. Materials and Methods. The work has been performed on 42 white rats of line...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Saratov State Medical University
2014-12-01
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| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2014_04_596-600.pdf |
| _version_ | 1819139719955480576 |
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| author | Alexandrov D.A. Timoshina P.A. Tuchin V.V. Maslyakova G.N. Palatova T.V. Skorokhod A.A. Lukashevich K.A. Yarovoy A.S.. |
| author_facet | Alexandrov D.A. Timoshina P.A. Tuchin V.V. Maslyakova G.N. Palatova T.V. Skorokhod A.A. Lukashevich K.A. Yarovoy A.S.. |
| author_sort | Alexandrov D.A. |
| collection | DOAJ |
| description | The purpose: to establish influence of a full ischemia of different duration and the subsequent reperfusionon pathology development in pancreas of rats by means of laser speckle-visualization and lifetime digital microscopy. Materials and Methods. The work has been performed on 42 white rats of line Wistar in weight of 200-250 Research of properties of a blood-groove was made by means of methods laser Doppler flowmetry, digital biomicroscopy and a method of laser speckle-contrast visualization. Results. After the termination of a 5-minute full ischemia the speed of bloodflow has been increased in 2-3 times, clinic pancreatic necrosis is marked does not develop. After the termination of 20-minute full ischemia the increase in speed of a bloodflow did not occur, there were morphological and clinical signs of pancreatic necrosis. Conclusion, the efficiency of monitoring of microhemodynamics of pancreas in rats by the method of speckle-capillary of full field has been shown. Multidirectional phase of perfusion changes in pancreas have been revealed after reversible infringement of blood supply of different duration. |
| first_indexed | 2024-12-22T11:27:08Z |
| format | Article |
| id | doaj.art-2c79a62c5973472d9674d2bd2badb264 |
| institution | Directory Open Access Journal |
| issn | 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-22T11:27:08Z |
| publishDate | 2014-12-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-2c79a62c5973472d9674d2bd2badb2642022-12-21T18:27:43ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182014-12-011045966003833Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreasAlexandrov D.A.0Timoshina P.A.1Tuchin V.V.2Maslyakova G.N.3Palatova T.V.4Skorokhod A.A.5Lukashevich K.A.6Yarovoy A.S..7Saratov state universitySaratov state universitySaratov state universitySaratov state universitySaratov state universitySaratov state universitySaratov state universitySaratov state universityThe purpose: to establish influence of a full ischemia of different duration and the subsequent reperfusionon pathology development in pancreas of rats by means of laser speckle-visualization and lifetime digital microscopy. Materials and Methods. The work has been performed on 42 white rats of line Wistar in weight of 200-250 Research of properties of a blood-groove was made by means of methods laser Doppler flowmetry, digital biomicroscopy and a method of laser speckle-contrast visualization. Results. After the termination of a 5-minute full ischemia the speed of bloodflow has been increased in 2-3 times, clinic pancreatic necrosis is marked does not develop. After the termination of 20-minute full ischemia the increase in speed of a bloodflow did not occur, there were morphological and clinical signs of pancreatic necrosis. Conclusion, the efficiency of monitoring of microhemodynamics of pancreas in rats by the method of speckle-capillary of full field has been shown. Multidirectional phase of perfusion changes in pancreas have been revealed after reversible infringement of blood supply of different duration.http://www.ssmj.ru/system/files/2014_04_596-600.pdfpancreasreperfusionspeckle imaging |
| spellingShingle | Alexandrov D.A. Timoshina P.A. Tuchin V.V. Maslyakova G.N. Palatova T.V. Skorokhod A.A. Lukashevich K.A. Yarovoy A.S.. Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas Саратовский научно-медицинский журнал pancreas reperfusion speckle imaging |
| title | Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas |
| title_full | Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas |
| title_fullStr | Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas |
| title_full_unstemmed | Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas |
| title_short | Dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas |
| title_sort | dynamics of laser speckle imaging of blood flow and morphological changes in tissues with a full time local ischemia of pancreas |
| topic | pancreas reperfusion speckle imaging |
| url | http://www.ssmj.ru/system/files/2014_04_596-600.pdf |
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