Modulation of the antitumor immune response by cancer-associated fibroblasts: mechanisms and targeting strategies to hamper their immunosuppressive functions
Cancer-associated fibroblasts (CAFs) are highly heterogeneous players that shape the tumor microenvironment and influence tumor progression, metastasis formation, and response to conventional therapies. During the past years, some CAFs subsets have also been involved in the modulation of immune cell...
Main Author: | Jerome Thiery |
---|---|
Format: | Article |
Language: | English |
Published: |
Open Exploration Publishing Inc.
2022-10-01
|
Series: | Exploration of Targeted Anti-tumor Therapy |
Subjects: | |
Online Access: | https://www.explorationpub.com/Journals/etat/Article/1002103 |
Similar Items
-
Immune checkpoint inhibitors as mediators for immunosuppression by cancer-associated fibroblasts: A comprehensive review
by: Fatemeh Eskandari-Malayeri, et al.
Published: (2022-10-01) -
Modulation of Immune Infiltration of Ovarian Cancer Tumor Microenvironment by Specific Subpopulations of Fibroblasts
by: Ji Wang, et al.
Published: (2020-10-01) -
Metabolic reprogramming and crosstalk of cancer-related fibroblasts and immune cells in the tumor microenvironment
by: Yifei Zhu, et al.
Published: (2022-08-01) -
Comprehensive analyses of the cancer-associated fibroblast subtypes and their score system for prediction of outcomes and immunosuppressive microenvironment in prostate cancer
by: Ze Gao, et al.
Published: (2024-04-01) -
Dissecting the role of cancer‐associated fibroblast‐derived biglycan as a potential therapeutic target in immunotherapy resistance: A tumor bulk and single‐cell transcriptomic study
by: Shaoquan Zheng, et al.
Published: (2023-02-01)