The Discordance Between HER-2/NEU Expression Assessed by Immunohistochemistry (IHC) and Fluorescence in Situ Hybridization (FISH): Is It Important to Detect?

The Discordance Between HER-2/NEU Expression Assessed by Immunohistochemistry (IHC) and Fluorescence in Situ Hybridization (FISH): Is It Important to Detect?

Purpose: Assessment of HER-2 has become of great importance following the advent of HER-2 antibody treatment. Use of trastuzumab therapy depends on the assessment of HER-2 via standard immunohistochemistry (IHC) assays for protein overexpression or via fluorescence in situ hybridization (FISH) for g...

Full description

Bibliographic Details
Main Authors: Berna Bozkurt Duman, Berksoy Sahin, Oguz Ismail Kara, Melek Erkisi, Adem Kidik, Melek Ergin, Emine Kilic Bagir
Format: Article
Language:English
Published: Cukurova University 2014-02-01
Series:Çukurova Üniversitesi Tıp Fakültesi Dergisi
Subjects:
Breast cancer; HER-2/neu; IHC; FISH; discordance rate
Online Access:http://www.scopemed.org/fulltextpdf.php?mno=39326

Similar Items

Similar Items