Culture-negative fungal endocarditis
A 54-year-old female, known case of hypertension and diabetes mellitus (controlled), was admitted with prolonged fever for 1½ months. On evaluation, fever workup was inconclusive and multiple cultures were negative. On re-assessment of history, she gave a history of cardiac catheterization 1 month b...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Heart and Mind |
| Subjects: | |
| Online Access: | http://www.heartmindjournal.org/article.asp?issn=2468-6476;year=2019;volume=3;issue=1;spage=27;epage=30;aulast=Kumar |
| _version_ | 1819155863061921792 |
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| author | Rohit Kumar J Kirtana Parul Kodan Yogiraj Ray Prabhat Kumar Ashutosh Biswas |
| author_facet | Rohit Kumar J Kirtana Parul Kodan Yogiraj Ray Prabhat Kumar Ashutosh Biswas |
| author_sort | Rohit Kumar |
| collection | DOAJ |
| description | A 54-year-old female, known case of hypertension and diabetes mellitus (controlled), was admitted with prolonged fever for 1½ months. On evaluation, fever workup was inconclusive and multiple cultures were negative. On re-assessment of history, she gave a history of cardiac catheterization 1 month back. Further evaluation revealed aortic valve vegetation on two-dimensional echo with raised beta-D glucan levels. She was managed with antifungal therapy followed by valve replacement surgery. The patient improved following the management and is doing fine. This case highlights the importance of detailed history-taking and evaluation. It also highlights the not uncommon occurrence of fungal endocarditis in patients with healthcare contact and the role of biomarkers as surrogate in case of culture-negative endocarditis. |
| first_indexed | 2024-12-22T15:43:44Z |
| format | Article |
| id | doaj.art-2c85a476a7dd4f41a837fb3fa64eee10 |
| institution | Directory Open Access Journal |
| issn | 2468-6476 2468-6484 |
| language | English |
| last_indexed | 2024-12-22T15:43:44Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Heart and Mind |
| spelling | doaj.art-2c85a476a7dd4f41a837fb3fa64eee102022-12-21T18:21:05ZengWolters Kluwer Medknow PublicationsHeart and Mind2468-64762468-64842019-01-0131273010.4103/hm.hm_31_19Culture-negative fungal endocarditisRohit KumarJ KirtanaParul KodanYogiraj RayPrabhat KumarAshutosh BiswasA 54-year-old female, known case of hypertension and diabetes mellitus (controlled), was admitted with prolonged fever for 1½ months. On evaluation, fever workup was inconclusive and multiple cultures were negative. On re-assessment of history, she gave a history of cardiac catheterization 1 month back. Further evaluation revealed aortic valve vegetation on two-dimensional echo with raised beta-D glucan levels. She was managed with antifungal therapy followed by valve replacement surgery. The patient improved following the management and is doing fine. This case highlights the importance of detailed history-taking and evaluation. It also highlights the not uncommon occurrence of fungal endocarditis in patients with healthcare contact and the role of biomarkers as surrogate in case of culture-negative endocarditis.http://www.heartmindjournal.org/article.asp?issn=2468-6476;year=2019;volume=3;issue=1;spage=27;epage=30;aulast=Kumarbiomarkerscaspofunginendocarditis |
| spellingShingle | Rohit Kumar J Kirtana Parul Kodan Yogiraj Ray Prabhat Kumar Ashutosh Biswas Culture-negative fungal endocarditis Heart and Mind biomarkers caspofungin endocarditis |
| title | Culture-negative fungal endocarditis |
| title_full | Culture-negative fungal endocarditis |
| title_fullStr | Culture-negative fungal endocarditis |
| title_full_unstemmed | Culture-negative fungal endocarditis |
| title_short | Culture-negative fungal endocarditis |
| title_sort | culture negative fungal endocarditis |
| topic | biomarkers caspofungin endocarditis |
| url | http://www.heartmindjournal.org/article.asp?issn=2468-6476;year=2019;volume=3;issue=1;spage=27;epage=30;aulast=Kumar |
| work_keys_str_mv | AT rohitkumar culturenegativefungalendocarditis AT jkirtana culturenegativefungalendocarditis AT parulkodan culturenegativefungalendocarditis AT yogirajray culturenegativefungalendocarditis AT prabhatkumar culturenegativefungalendocarditis AT ashutoshbiswas culturenegativefungalendocarditis |