TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?
Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly all carcinogenesis hallmarks. Recently, they ha...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-09-01
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| Series: | Membranes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0375/13/9/788 |
| _version_ | 1797578865967628288 |
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| author | Mayar Soussi Alice Hasselsweiller Dimitra Gkika |
| author_facet | Mayar Soussi Alice Hasselsweiller Dimitra Gkika |
| author_sort | Mayar Soussi |
| collection | DOAJ |
| description | Breast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly all carcinogenesis hallmarks. Recently, they have also emerged as important actors in resistance to therapy by modulating the response to various pharmaceutical agents. Targeting TRP channels may represent a promising approach to overcome resistance to therapies in breast cancer patients. |
| first_indexed | 2024-03-10T22:28:47Z |
| format | Article |
| id | doaj.art-2c88c3f5e87645e5bfb5c24aa9820ccd |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-10T22:28:47Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-2c88c3f5e87645e5bfb5c24aa9820ccd2023-11-19T11:54:27ZengMDPI AGMembranes2077-03752023-09-0113978810.3390/membranes13090788TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance?Mayar Soussi0Alice Hasselsweiller1Dimitra Gkika2Univ. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277—CANTHER—Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, FranceUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277—CANTHER—Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, FranceUniv. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277—CANTHER—Cancer Heterogeneity Plasticity and Resistance to Therapies, F-59000 Lille, FranceBreast cancer is a major health concern worldwide, and resistance to therapies remains a significant challenge in treating this disease. In breast cancer, Transient Receptor Potential (TRP) channels are well studied and constitute key players in nearly all carcinogenesis hallmarks. Recently, they have also emerged as important actors in resistance to therapy by modulating the response to various pharmaceutical agents. Targeting TRP channels may represent a promising approach to overcome resistance to therapies in breast cancer patients.https://www.mdpi.com/2077-0375/13/9/788breast cancerTRP channelschemotherapychemoresistance taxanesanthracyclinestamoxifen |
| spellingShingle | Mayar Soussi Alice Hasselsweiller Dimitra Gkika TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? Membranes breast cancer TRP channels chemotherapy chemoresistance taxanes anthracyclines tamoxifen |
| title | TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? |
| title_full | TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? |
| title_fullStr | TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? |
| title_full_unstemmed | TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? |
| title_short | TRP Channels: The Neglected Culprits in Breast Cancer Chemotherapy Resistance? |
| title_sort | trp channels the neglected culprits in breast cancer chemotherapy resistance |
| topic | breast cancer TRP channels chemotherapy chemoresistance taxanes anthracyclines tamoxifen |
| url | https://www.mdpi.com/2077-0375/13/9/788 |
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