Study of some parameters of blood coagulation in patients with rheumatoid arthritis

Rheumatoid arthritis represents one of actual problems of modern rheumatology. Disease is shown by symmetric defeat of joints, extraarticular changes, in pathogenesis of which leading part belong combined to shifts as a part of cellular and humoral immunity links. In the majority of works correlatio...

Full description

Bibliographic Details
Main Author: Nuritdinova S. K.
Format: Article
Language:Russian
Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2010-01-01
Series:Морфологія
Subjects:
Online Access:http://www.morphology.dp.ua/_pub/MORPHO-2010-04-03/10nskbra.pdf
_version_ 1818237604725784576
author Nuritdinova S. K.
author_facet Nuritdinova S. K.
author_sort Nuritdinova S. K.
collection DOAJ
description Rheumatoid arthritis represents one of actual problems of modern rheumatology. Disease is shown by symmetric defeat of joints, extraarticular changes, in pathogenesis of which leading part belong combined to shifts as a part of cellular and humoral immunity links. In the majority of works correlation between clinical features and indicators of coagulation system was not studied at rheumatoid arthritis. Aim: the studying of some indicators of blood curling system and their clinical- pathogenetic importance at patients with rheumatoid arthritis. Material and methods: In total there were examined 73 patients at the age from 21 till 60 years with duration of disease from 2 till 10 years, with diagnosis rheumatoid arthritis, which have been divided by degree of activity, stages RА, the articulate form and systemic manifestations. All patients with rheumatoid arthritis estimated a condition of coagulation system: defined thromboplastin-SI, activated partial thromboplastin time, fibrinogen, the international normalised relation. Results: at patients with rheumatoid arthritis there were increase of indicators of defined thromboplastin-SI, blood level of fibrinogen, decrease the international normalised relation, shortening the activated partial thromboplastin time that specifies the increasing of activity of coagulation system.
first_indexed 2024-12-12T12:28:24Z
format Article
id doaj.art-2c895f93a79a4743a156c5f9f5b66195
institution Directory Open Access Journal
issn 1997-9665
language Russian
last_indexed 2024-12-12T12:28:24Z
publishDate 2010-01-01
publisher Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy
record_format Article
series Морфологія
spelling doaj.art-2c895f93a79a4743a156c5f9f5b661952022-12-22T00:24:28ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96652010-01-01432831Study of some parameters of blood coagulation in patients with rheumatoid arthritisNuritdinova S. K.Rheumatoid arthritis represents one of actual problems of modern rheumatology. Disease is shown by symmetric defeat of joints, extraarticular changes, in pathogenesis of which leading part belong combined to shifts as a part of cellular and humoral immunity links. In the majority of works correlation between clinical features and indicators of coagulation system was not studied at rheumatoid arthritis. Aim: the studying of some indicators of blood curling system and their clinical- pathogenetic importance at patients with rheumatoid arthritis. Material and methods: In total there were examined 73 patients at the age from 21 till 60 years with duration of disease from 2 till 10 years, with diagnosis rheumatoid arthritis, which have been divided by degree of activity, stages RА, the articulate form and systemic manifestations. All patients with rheumatoid arthritis estimated a condition of coagulation system: defined thromboplastin-SI, activated partial thromboplastin time, fibrinogen, the international normalised relation. Results: at patients with rheumatoid arthritis there were increase of indicators of defined thromboplastin-SI, blood level of fibrinogen, decrease the international normalised relation, shortening the activated partial thromboplastin time that specifies the increasing of activity of coagulation system.http://www.morphology.dp.ua/_pub/MORPHO-2010-04-03/10nskbra.pdfrheumatoid arthritisblood coagulation systemthromboplastinactivated partial thromboplastin timefibrinogen
spellingShingle Nuritdinova S. K.
Study of some parameters of blood coagulation in patients with rheumatoid arthritis
Морфологія
rheumatoid arthritis
blood coagulation system
thromboplastin
activated partial thromboplastin time
fibrinogen
title Study of some parameters of blood coagulation in patients with rheumatoid arthritis
title_full Study of some parameters of blood coagulation in patients with rheumatoid arthritis
title_fullStr Study of some parameters of blood coagulation in patients with rheumatoid arthritis
title_full_unstemmed Study of some parameters of blood coagulation in patients with rheumatoid arthritis
title_short Study of some parameters of blood coagulation in patients with rheumatoid arthritis
title_sort study of some parameters of blood coagulation in patients with rheumatoid arthritis
topic rheumatoid arthritis
blood coagulation system
thromboplastin
activated partial thromboplastin time
fibrinogen
url http://www.morphology.dp.ua/_pub/MORPHO-2010-04-03/10nskbra.pdf
work_keys_str_mv AT nuritdinovask studyofsomeparametersofbloodcoagulationinpatientswithrheumatoidarthritis