CTCF acetylation at lysine 20 is required for the early cardiac mesoderm differentiation of embryonic stem cells

Abstract The CCCTC-binding factor (CTCF) protein and its modified forms regulate gene expression and genome organization. However, information on CTCF acetylation and its biological function is still lacking. Here, we show that CTCF can be acetylated at lysine 20 (CTCF-K20) by CREB-binding protein (...

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Detaylı Bibliyografya
Asıl Yazarlar: Shixin Gong, Gongcheng Hu, Rong Guo, Jie Zhang, Yiqi Yang, Binrui Ji, Gang Li, Hongjie Yao
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: SpringerOpen 2022-09-01
Seri Bilgileri:Cell Regeneration
Konular:
Online Erişim:https://doi.org/10.1186/s13619-022-00131-w