Features of Pancreatic Pathology in Children

Background. The prevalence of pancreatitis in children with digestive disorders is 5–25 %. Aim of research: to determine the prevalence of pancreatic pathology in children. Material and methods. The research was conducted on the basis of department of gastroenterology of Chernivtsi Regional Clinical...

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Main Authors: T.V. Sorokman, O.-M.V. Popelyuk
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2016-11-01
Series:Gastroenterologìa
Subjects:
Online Access:http://gastro.zaslavsky.com.ua/article/view/81093
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author T.V. Sorokman
O.-M.V. Popelyuk
author_facet T.V. Sorokman
O.-M.V. Popelyuk
author_sort T.V. Sorokman
collection DOAJ
description Background. The prevalence of pancreatitis in children with digestive disorders is 5–25 %. Aim of research: to determine the prevalence of pancreatic pathology in children. Material and methods. The research was conducted on the basis of department of gastroenterology of Chernivtsi Regional Clinical Children’s Hospital during 2013–2015. Results. The overall prevalence of chronic pancreatitis in children of Chernivtsi region is 1.8 %. It should also be noted that 66 % of children with chronic gastroduodenitis and 100 % of children with duodenal bulb ulcer had ultrasound changes of pancreas. Signs of chronic pancreatitis were detected in 1 child with celiac disease and 4 children with lactose intolerance; 17 children had identified ultrasound signs of pancreatic fibrosis, and reduced elastase‑1 in stool, which can be considered as signs of chronic pancreatitis; 9 children had identified ultrasound signs of structural changes of pancreas, but the level of elastase‑1 was normal (patients with recurrent pancreatitis); 18 children had no ultrasound changes of pancreas and no deviation in the structure and the level of elastase‑1. Conclusion. The chronic pancreatitis in children is often associated with pain (epigastric paroxysmal pain with frequent changes of pain location), dyspeptic (often manifested by nausea and vo­miting) and astheno-vegetative syndromes which are associated with disharmonious physical development. All patients with chronic pancreatitis were revealed to have focal or linear fibrotic changes in the parenchyma of the pancreas, nonspecific changes in coprogram and a significant reduction of elastase‑1 level in blood.
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spelling doaj.art-2c8dab54ae4946918518d7ab9d9a7b7d2022-12-21T23:49:26ZengZaslavsky O.Yu.Gastroenterologìa2308-20972518-78802016-11-01504.62434610.22141/2308-2097.4.62.2016.8109381093Features of Pancreatic Pathology in ChildrenT.V. Sorokman0O.-M.V. Popelyuk1HSEIU «Bukovinian State Medical University», ChernivtsiHSEIU «Bukovinian State Medical University», ChernivtsiBackground. The prevalence of pancreatitis in children with digestive disorders is 5–25 %. Aim of research: to determine the prevalence of pancreatic pathology in children. Material and methods. The research was conducted on the basis of department of gastroenterology of Chernivtsi Regional Clinical Children’s Hospital during 2013–2015. Results. The overall prevalence of chronic pancreatitis in children of Chernivtsi region is 1.8 %. It should also be noted that 66 % of children with chronic gastroduodenitis and 100 % of children with duodenal bulb ulcer had ultrasound changes of pancreas. Signs of chronic pancreatitis were detected in 1 child with celiac disease and 4 children with lactose intolerance; 17 children had identified ultrasound signs of pancreatic fibrosis, and reduced elastase‑1 in stool, which can be considered as signs of chronic pancreatitis; 9 children had identified ultrasound signs of structural changes of pancreas, but the level of elastase‑1 was normal (patients with recurrent pancreatitis); 18 children had no ultrasound changes of pancreas and no deviation in the structure and the level of elastase‑1. Conclusion. The chronic pancreatitis in children is often associated with pain (epigastric paroxysmal pain with frequent changes of pain location), dyspeptic (often manifested by nausea and vo­miting) and astheno-vegetative syndromes which are associated with disharmonious physical development. All patients with chronic pancreatitis were revealed to have focal or linear fibrotic changes in the parenchyma of the pancreas, nonspecific changes in coprogram and a significant reduction of elastase‑1 level in blood.http://gastro.zaslavsky.com.ua/article/view/81093childrenpancreatic pathologychronic pancreatitis
spellingShingle T.V. Sorokman
O.-M.V. Popelyuk
Features of Pancreatic Pathology in Children
Gastroenterologìa
children
pancreatic pathology
chronic pancreatitis
title Features of Pancreatic Pathology in Children
title_full Features of Pancreatic Pathology in Children
title_fullStr Features of Pancreatic Pathology in Children
title_full_unstemmed Features of Pancreatic Pathology in Children
title_short Features of Pancreatic Pathology in Children
title_sort features of pancreatic pathology in children
topic children
pancreatic pathology
chronic pancreatitis
url http://gastro.zaslavsky.com.ua/article/view/81093
work_keys_str_mv AT tvsorokman featuresofpancreaticpathologyinchildren
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