Electron transfer between cytochrome c and microsomal monooxygenase generates reactive oxygen species that accelerates apoptosis

Generation of reactive oxygen species (ROS) are possibly induced by the crosstalk between mitochondria and endoplasmic reticula, which is physiologically important in apoptosis. Cytochrome c (Cyt c) is believed to play a crucial role in such signaling pathway by interrupting the coupling within micr...

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Bibliographic Details
Main Authors: Han Xie, Li Song, Sagie Katz, Jinyu Zhu, Yawen Liu, Jinping Tang, Linjun Cai, Peter Hildebrandt, Xiao Xia Han
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231722001124