FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006

BACKGROUND AND OBJECTIVE: The premarital screening of β-thalassemia was performed all over the county of Iran from 1997. Although this program can reduce the large number of children born with thalassemia, we are still witness to the birth of these children. The aim of this study was to survey the a...

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Main Authors: SR Hosseini, E Yaghoubi, M Ghanbari, A Bijani
Format: Article
Language:English
Published: Babol University of Medical Sciences 2008-01-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Subjects:
Online Access:http://jbums.org/article-1-2493-en.html
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author SR Hosseini
E Yaghoubi,
M Ghanbari
A Bijani
author_facet SR Hosseini
E Yaghoubi,
M Ghanbari
A Bijani
author_sort SR Hosseini
collection DOAJ
description BACKGROUND AND OBJECTIVE: The premarital screening of β-thalassemia was performed all over the county of Iran from 1997. Although this program can reduce the large number of children born with thalassemia, we are still witness to the birth of these children. The aim of this study was to survey the associated factors accompanied with the birth of children with thalassemia major in Babol, Iran during 1997-2006 in spite of this screening program.METHODS: This study was conducted on all parents of children with beta thalassemia major as case group and the carrier couples who had no child with thalassemia major as control group from 1997-2006. Data including age, sex, relations, insurance condition, screening condition, PND (prenatal diagnosis) condition, consultation and education about thalassemia were collected by a questionnaire and then analyzed.FINDINGS: Comparing two groups, the following results were obtained: being insured in control group was 5.6 (CI=2.3-13.8) times more than case group (p<0.001). Continuous care before pregnancy in control group was 95.8 times more than case group (OR=95.8, CI=18.5-496, p<0.001). Considering family relation there was not significant relationship between two groups. The trained couples in control group were 33 times more than case group (OR= 33, CI= 7-153, p<0.001). After bring all variables in logistic regression model, the most effect is related to the education about thalassemia, continuous cares and being insured, respectively (p<0.0001). CONCLUSION: The results of this study showed that education about thalassemia, continuous care after marriage, thalassemia consultations, and being insured are the important factors to decrease the birth rate of the children suffering from major thalassemia.
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spelling doaj.art-2c92de61722142fe91767ff452e30d072022-12-21T19:29:57ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702008-01-01964449FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006SR Hosseini0E Yaghoubi,1M Ghanbari2A Bijani3 BACKGROUND AND OBJECTIVE: The premarital screening of β-thalassemia was performed all over the county of Iran from 1997. Although this program can reduce the large number of children born with thalassemia, we are still witness to the birth of these children. The aim of this study was to survey the associated factors accompanied with the birth of children with thalassemia major in Babol, Iran during 1997-2006 in spite of this screening program.METHODS: This study was conducted on all parents of children with beta thalassemia major as case group and the carrier couples who had no child with thalassemia major as control group from 1997-2006. Data including age, sex, relations, insurance condition, screening condition, PND (prenatal diagnosis) condition, consultation and education about thalassemia were collected by a questionnaire and then analyzed.FINDINGS: Comparing two groups, the following results were obtained: being insured in control group was 5.6 (CI=2.3-13.8) times more than case group (p<0.001). Continuous care before pregnancy in control group was 95.8 times more than case group (OR=95.8, CI=18.5-496, p<0.001). Considering family relation there was not significant relationship between two groups. The trained couples in control group were 33 times more than case group (OR= 33, CI= 7-153, p<0.001). After bring all variables in logistic regression model, the most effect is related to the education about thalassemia, continuous cares and being insured, respectively (p<0.0001). CONCLUSION: The results of this study showed that education about thalassemia, continuous care after marriage, thalassemia consultations, and being insured are the important factors to decrease the birth rate of the children suffering from major thalassemia.http://jbums.org/article-1-2493-en.htmlβ thalassemia majorpreventionfactors
spellingShingle SR Hosseini
E Yaghoubi,
M Ghanbari
A Bijani
FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
β thalassemia major
prevention
factors
title FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006
title_full FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006
title_fullStr FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006
title_full_unstemmed FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006
title_short FACTORS RELATED TO THE BIRTH OF CHILDREN WITH THALASSEMIA MAJOR IN BABOL DURING 1997-2006
title_sort factors related to the birth of children with thalassemia major in babol during 1997 2006
topic β thalassemia major
prevention
factors
url http://jbums.org/article-1-2493-en.html
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AT mghanbari factorsrelatedtothebirthofchildrenwiththalassemiamajorinbabolduring19972006
AT abijani factorsrelatedtothebirthofchildrenwiththalassemiamajorinbabolduring19972006