Ten-eleven translocation 1 mediating DNA demethylation regulates the proliferation of chicken primordial germ cells through the activation of Wnt4/β-catenin signaling pathway

Ten-eleven translocation 1 mediating DNA demethylation regulates the proliferation of chicken primordial germ cells through the activation of Wnt4/β-catenin signaling pathway

Objective The objective of this study was to investigate the regulation relationship of Ten-eleven translocation 1 (Tet1) in DNA demethylation and the proliferation of primordial germ cells (PGCs) in chickens. Methods siRNA targeting Tet1 was used to transiently knockdown the expression of Tet1 in c...

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Bibliographic Details
Main Authors: Yinglin Lu, Ming Li, Heng Cao, Jing Zhou, Fan Li, Debing Yu, Minli Yu
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2024-03-01
Series:Animal Bioscience
Subjects:
β-catenin
demethylation
primordial germ cells (pgcs)
proliferation
ten-eleven translocation 1 ()
Online Access:http://www.animbiosci.org/upload/pdf/ab-23-0310.pdf

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