Mineralocorticoid Receptor Signaling in the Inflammatory Skeletal Muscle Microenvironments of Muscular Dystrophy and Acute Injury

Mineralocorticoid Receptor Signaling in the Inflammatory Skeletal Muscle Microenvironments of Muscular Dystrophy and Acute Injury

Duchenne muscular dystrophy (DMD) is a striated muscle degenerative disease due to loss of functional dystrophin protein. Loss of dystrophin results in susceptibility of muscle membranes to damage, leading to muscle degeneration and continuous inflammation and fibrosis that further exacerbate pathol...

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Bibliographic Details
Main Authors:	Zachary M. Howard, Chetan K. Gomatam, Arden B. Piepho, Jill A. Rafael-Fortney
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Series:	Frontiers in Pharmacology
Subjects:	aldosterone muscular dystrophy inflammation myeloid cells skeletal muscle mineralocorticoid receptor
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.942660/full

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