Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient

Introduction Most patients admitted to hospital recover with treatments that can be administered on the general ward. A small but important group deteriorate however and require augmented organ support in areas with increased nursing to patient ratios. In observational studies evaluating this cohort...

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Main Authors: Oliver C Redfern, Duncan Young, Peter J Watkinson, James Malycha, Guy Ludbrook, Christian Subbe, Daryl Jones, Arthas Flabouris, Chris Andersen, Sandra Peake, Lukah Dykes, Adam Phillips
Format: Article
Language:English
Published: BMJ Publishing Group 2022-09-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/9/e057614.full
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author Oliver C Redfern
Duncan Young
Peter J Watkinson
James Malycha
Guy Ludbrook
Christian Subbe
Daryl Jones
Arthas Flabouris
Chris Andersen
Sandra Peake
Lukah Dykes
Adam Phillips
author_facet Oliver C Redfern
Duncan Young
Peter J Watkinson
James Malycha
Guy Ludbrook
Christian Subbe
Daryl Jones
Arthas Flabouris
Chris Andersen
Sandra Peake
Lukah Dykes
Adam Phillips
author_sort Oliver C Redfern
collection DOAJ
description Introduction Most patients admitted to hospital recover with treatments that can be administered on the general ward. A small but important group deteriorate however and require augmented organ support in areas with increased nursing to patient ratios. In observational studies evaluating this cohort, proxy outcomes such as unplanned intensive care unit admission, cardiac arrest and death are used. These outcome measures introduce subjectivity and variability, which in turn hinders the development and accuracy of the increasing numbers of electronic medical record (EMR) linked digital tools designed to predict clinical deterioration. Here, we describe a protocol for developing a new outcome measure using mixed methods to address these limitations.Methods and analysis We will undertake firstly, a systematic literature review to identify existing generic, syndrome-specific and organ-specific definitions for clinically deteriorated, hospitalised adult patients. Secondly, an international modified Delphi study to generate a short list of candidate definitions. Thirdly, a nominal group technique (NGT) (using a trained facilitator) will take a diverse group of stakeholders through a structured process to generate a consensus definition. The NGT process will be informed by the data generated from the first two stages. The definition(s) for the deteriorated ward patient will be readily extractable from the EMR.Ethics and dissemination This study has ethics approval (reference 16399) from the Central Adelaide Local Health Network Human Research Ethics Committee. Results generated from this study will be disseminated through publication and presentation at national and international scientific meetings.
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spelling doaj.art-2c967808d60a429f9327626551671b172022-12-22T02:35:39ZengBMJ Publishing GroupBMJ Open2044-60552022-09-0112910.1136/bmjopen-2021-057614Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patientOliver C Redfern0Duncan Young1Peter J Watkinson2James Malycha3Guy Ludbrook4Christian Subbe5Daryl Jones6Arthas Flabouris7Chris Andersen8Sandra Peake9Lukah Dykes10Adam Phillips11Kadoorie Centre for Critical Care Research and Education, University of Oxford, Oxford, Oxfordshire, UKKadoorie Centre for Critical Care Research and Education, University of Oxford, Oxford, Oxfordshire, UKKadoorie Centre for Critical Care Research and Education, University of Oxford, Oxford, Oxfordshire, UKIntensive Care Unit, The Queen Elizabeth Hospital, Woodville South, South Australia, AustraliaDepartment of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, AustraliaSchool of Medical Sciences, Bangor University, Bangor, Gwynedd, UKIntensive Care Unit Austin Hospital, Austin Health, Heidelberg, Victoria, AustraliaDepartment of Acute Care Medicine, The University of Adelaide, Adelaide, South Australia, AustraliaCritical Care Program, The George Institute for Global Health, Newtown, New South Wales, AustraliaIntensive Care Unit, The Queen Elizabeth Hospital, Woodville South, South Australia, AustraliaFlinders University, Adelaide, South Australia, AustraliaUniversity of South Australia, Adelaide, South Australia, AustraliaIntroduction Most patients admitted to hospital recover with treatments that can be administered on the general ward. A small but important group deteriorate however and require augmented organ support in areas with increased nursing to patient ratios. In observational studies evaluating this cohort, proxy outcomes such as unplanned intensive care unit admission, cardiac arrest and death are used. These outcome measures introduce subjectivity and variability, which in turn hinders the development and accuracy of the increasing numbers of electronic medical record (EMR) linked digital tools designed to predict clinical deterioration. Here, we describe a protocol for developing a new outcome measure using mixed methods to address these limitations.Methods and analysis We will undertake firstly, a systematic literature review to identify existing generic, syndrome-specific and organ-specific definitions for clinically deteriorated, hospitalised adult patients. Secondly, an international modified Delphi study to generate a short list of candidate definitions. Thirdly, a nominal group technique (NGT) (using a trained facilitator) will take a diverse group of stakeholders through a structured process to generate a consensus definition. The NGT process will be informed by the data generated from the first two stages. The definition(s) for the deteriorated ward patient will be readily extractable from the EMR.Ethics and dissemination This study has ethics approval (reference 16399) from the Central Adelaide Local Health Network Human Research Ethics Committee. Results generated from this study will be disseminated through publication and presentation at national and international scientific meetings.https://bmjopen.bmj.com/content/12/9/e057614.full
spellingShingle Oliver C Redfern
Duncan Young
Peter J Watkinson
James Malycha
Guy Ludbrook
Christian Subbe
Daryl Jones
Arthas Flabouris
Chris Andersen
Sandra Peake
Lukah Dykes
Adam Phillips
Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
BMJ Open
title Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
title_full Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
title_fullStr Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
title_full_unstemmed Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
title_short Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
title_sort protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient
url https://bmjopen.bmj.com/content/12/9/e057614.full
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