Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis
BackgroundCoronary atherosclerotic heart disease is one of the most serious health and life-threatening diseases. There is no doubt that despite the increasing number of assessment methods used clinically, the prognosis assessment is still not ideal, and newer assessment methods are needed.Objective...
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| Format: | Article |
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Frontiers Media S.A.
2023-08-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1164290/full |
| _version_ | 1797752069626527744 |
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| author | Huaigang Chen Huaigang Chen Lang Hong Gang Xi Hong Wang Jing Hu Qi Liu Qi Liu Liu Yang |
| author_facet | Huaigang Chen Huaigang Chen Lang Hong Gang Xi Hong Wang Jing Hu Qi Liu Qi Liu Liu Yang |
| author_sort | Huaigang Chen |
| collection | DOAJ |
| description | BackgroundCoronary atherosclerotic heart disease is one of the most serious health and life-threatening diseases. There is no doubt that despite the increasing number of assessment methods used clinically, the prognosis assessment is still not ideal, and newer assessment methods are needed.ObjectiveTo investigate the predictive value of quantitative flow ratio (QFR) for adverse events (vessel-oriented composite endpoint events/target lesion failure) in patients after percutaneous coronary intervention (PCI).MethodEight studies involving 4,173 patients (5,688 vascular lesions) were included. These are studies on the relationship between QFR values and prognosis of adverse cardiac events after PCI. This meta-analysis was performed after quality assessment and data extraction of clinical trials data that met the inclusion criteria.ResultEach of the eight studies described the cut-off values for the best predictive ability of post-PCI QFR and the hazard ratio (HR) between QFR values and adverse events, respectively. The pooled HR of these studies was 4.72 (95% CI: 3.29–6.75). Concurrently, lower post-PCI QFR values were associated with the occurrence of individual clinical events (cardiac death/myocardial infarction/target vessel revascularization), with relative risk values of 6.51 (95% CI: 4.96–8.53), 4.83 (95% CI: 3.08–7.57), and 4.21 (95% CI: 2.66–6.68), respectively.ConclusionQFR may have great potential in the assessment of prognosis. It is necessary to measure QFR value after PCI. A lower QFR value after PCI was an important predictor for experiencing adverse events. |
| first_indexed | 2024-03-12T16:57:26Z |
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| id | doaj.art-2c97acf942574efb8ac06261a665a7f7 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-03-12T16:57:26Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-2c97acf942574efb8ac06261a665a7f72023-08-07T20:49:36ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-08-011010.3389/fcvm.2023.11642901164290Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysisHuaigang Chen0Huaigang Chen1Lang Hong2Gang Xi3Hong Wang4Jing Hu5Qi Liu6Qi Liu7Liu Yang8Medical College of Nanchang University, Nanchang, ChinaDepartment of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, ChinaDepartment of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, ChinaDepartment of Cardiology, The Third People's Hospital of Jingdezhen, Jingdezhen, ChinaDepartment of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, ChinaDepartment of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, ChinaMedical College of Nanchang University, Nanchang, ChinaDepartment of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, ChinaDepartment of Cardiology, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, ChinaBackgroundCoronary atherosclerotic heart disease is one of the most serious health and life-threatening diseases. There is no doubt that despite the increasing number of assessment methods used clinically, the prognosis assessment is still not ideal, and newer assessment methods are needed.ObjectiveTo investigate the predictive value of quantitative flow ratio (QFR) for adverse events (vessel-oriented composite endpoint events/target lesion failure) in patients after percutaneous coronary intervention (PCI).MethodEight studies involving 4,173 patients (5,688 vascular lesions) were included. These are studies on the relationship between QFR values and prognosis of adverse cardiac events after PCI. This meta-analysis was performed after quality assessment and data extraction of clinical trials data that met the inclusion criteria.ResultEach of the eight studies described the cut-off values for the best predictive ability of post-PCI QFR and the hazard ratio (HR) between QFR values and adverse events, respectively. The pooled HR of these studies was 4.72 (95% CI: 3.29–6.75). Concurrently, lower post-PCI QFR values were associated with the occurrence of individual clinical events (cardiac death/myocardial infarction/target vessel revascularization), with relative risk values of 6.51 (95% CI: 4.96–8.53), 4.83 (95% CI: 3.08–7.57), and 4.21 (95% CI: 2.66–6.68), respectively.ConclusionQFR may have great potential in the assessment of prognosis. It is necessary to measure QFR value after PCI. A lower QFR value after PCI was an important predictor for experiencing adverse events.https://www.frontiersin.org/articles/10.3389/fcvm.2023.1164290/fullcoronary heart diseasepercutaneous coronary interventionprognosismetaquantitative flow ratio |
| spellingShingle | Huaigang Chen Huaigang Chen Lang Hong Gang Xi Hong Wang Jing Hu Qi Liu Qi Liu Liu Yang Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis Frontiers in Cardiovascular Medicine coronary heart disease percutaneous coronary intervention prognosis meta quantitative flow ratio |
| title | Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis |
| title_full | Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis |
| title_fullStr | Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis |
| title_full_unstemmed | Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis |
| title_short | Prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy: a meta-analysis |
| title_sort | prognostic value of quantitative flow ratio in patients with coronary heart disease after percutaneous coronary intervention therapy a meta analysis |
| topic | coronary heart disease percutaneous coronary intervention prognosis meta quantitative flow ratio |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1164290/full |
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