Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves

Schefflera elliptica or locally called kayu tulak, is one of the Balinese herbal plants that have traditionally be used to reject (tulak) negative influences that exist in the human body. Althoug, S. elliptica has been routinely used as a part of a ritual in Bali, only a limited study has been repor...

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Main Authors: I Gede Yoga Ayuning Kirtanayasa, Anak Agung Gede Indraningrat, I Putu Candra
Format: Article
Language:English
Published: State Islamic University Sunan Kalijaga 2023-04-01
Series:Biology, Medicine & Natural Product Chemistry
Subjects:
Online Access:https://sciencebiology.org/index.php/BIOMEDICH/article/view/344
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author I Gede Yoga Ayuning Kirtanayasa
Anak Agung Gede Indraningrat
I Putu Candra
author_facet I Gede Yoga Ayuning Kirtanayasa
Anak Agung Gede Indraningrat
I Putu Candra
author_sort I Gede Yoga Ayuning Kirtanayasa
collection DOAJ
description Schefflera elliptica or locally called kayu tulak, is one of the Balinese herbal plants that have traditionally be used to reject (tulak) negative influences that exist in the human body. Althoug, S. elliptica has been routinely used as a part of a ritual in Bali, only a limited study has been reported on its bioactivity. This study was designed to analyze the phytochemical content, antibacterial activity, and antioxidant activity of S. elliptica. In this study, simplisia of S. elliptica was extracted using n-hexane and ethyl acetate solvents, then the viscous extracts of the two solvents were carried out for phytochemical tests, antibacterial activity tests with the Kirby-Bauer method and antioxidant activity tests with based on DPPH method. Phytochemical screening showed that the n-hexane extract contains active compounds in the form of phenols and steroids while ethyl acetate contains active compounds in the form of phenols, tannins, and steroids. Antibacterial screening showed ethyl acetate extract of S. elliptica displayed a diameter zone of inhibition of 10.72±0.71 mm against Staphylococcus aureus, 12.17±2.80 mm against Streptococcus mutans, 12.40±1.65 mm against Escherichia coli and 15.20±2.44 mm against Klebsiella pneumoniae. The DPPH analysis showed percentages of 61.17% and 67.42% from n-hexane and ethyl acetate extracts respectively, which indicated the antioxidant properties of S. elliptica. Overall, this research provides a preliminary report on the bioactivity potential of S. elliptica mainly in term of antibacterial and antioxidant properties which open up possibilities for future drug development.
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spelling doaj.art-2c97fe2227da4959b6c991520ed68c402023-08-12T12:49:11ZengState Islamic University Sunan KalijagaBiology, Medicine & Natural Product Chemistry2089-65142540-93282023-04-0112132933410.14421/biomedich.2023.121.329-334186Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica LeavesI Gede Yoga Ayuning Kirtanayasa0Anak Agung Gede Indraningrat1I Putu Candra2Warmadewa UniversityWarmadewa UniversityWarmadewa UniversitySchefflera elliptica or locally called kayu tulak, is one of the Balinese herbal plants that have traditionally be used to reject (tulak) negative influences that exist in the human body. Althoug, S. elliptica has been routinely used as a part of a ritual in Bali, only a limited study has been reported on its bioactivity. This study was designed to analyze the phytochemical content, antibacterial activity, and antioxidant activity of S. elliptica. In this study, simplisia of S. elliptica was extracted using n-hexane and ethyl acetate solvents, then the viscous extracts of the two solvents were carried out for phytochemical tests, antibacterial activity tests with the Kirby-Bauer method and antioxidant activity tests with based on DPPH method. Phytochemical screening showed that the n-hexane extract contains active compounds in the form of phenols and steroids while ethyl acetate contains active compounds in the form of phenols, tannins, and steroids. Antibacterial screening showed ethyl acetate extract of S. elliptica displayed a diameter zone of inhibition of 10.72±0.71 mm against Staphylococcus aureus, 12.17±2.80 mm against Streptococcus mutans, 12.40±1.65 mm against Escherichia coli and 15.20±2.44 mm against Klebsiella pneumoniae. The DPPH analysis showed percentages of 61.17% and 67.42% from n-hexane and ethyl acetate extracts respectively, which indicated the antioxidant properties of S. elliptica. Overall, this research provides a preliminary report on the bioactivity potential of S. elliptica mainly in term of antibacterial and antioxidant properties which open up possibilities for future drug development.https://sciencebiology.org/index.php/BIOMEDICH/article/view/344antibacterial, antioxidant, phytochemical, schefflera elliptica
spellingShingle I Gede Yoga Ayuning Kirtanayasa
Anak Agung Gede Indraningrat
I Putu Candra
Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves
Biology, Medicine & Natural Product Chemistry
antibacterial, antioxidant, phytochemical, schefflera elliptica
title Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves
title_full Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves
title_fullStr Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves
title_full_unstemmed Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves
title_short Phytochemical, Antibacterial and Antioxidant Activities of Schefflera elliptica Leaves
title_sort phytochemical antibacterial and antioxidant activities of schefflera elliptica leaves
topic antibacterial, antioxidant, phytochemical, schefflera elliptica
url https://sciencebiology.org/index.php/BIOMEDICH/article/view/344
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AT iputucandra phytochemicalantibacterialandantioxidantactivitiesofscheffleraellipticaleaves