The relation between ageing and increasing pulse pressure in upper and lower limbs

Background & Objective: Pulse pressure is a marker of arterial stiffness. In old age the pressure wave reflection also contribute to disparity of pulse pressure between upper and lower limbs. This study was done to determine the relation between ageing and increased pulse pressure of upper and l...

Full description

Bibliographic Details
Main Authors: Seyed Mehran Hosseini (MD, PhD), Ali Reza Maleki
Format: Article
Language:fas
Published: Golestan University of Medical Sciences 2009-05-01
Series:مجله دانشگاه علوم پزشکی گرگان
Subjects:
Online Access:http://goums.ac.ir/journal/browse.php?a_code=A-10-1-349&slc_lang=en&sid=1
_version_ 1811286233475710976
author Seyed Mehran Hosseini (MD, PhD)
Ali Reza Maleki
author_facet Seyed Mehran Hosseini (MD, PhD)
Ali Reza Maleki
author_sort Seyed Mehran Hosseini (MD, PhD)
collection DOAJ
description Background & Objective: Pulse pressure is a marker of arterial stiffness. In old age the pressure wave reflection also contribute to disparity of pulse pressure between upper and lower limbs. This study was done to determine the relation between ageing and increased pulse pressure of upper and lower limbs. Materials & Methods: In this discriptive study blood pressure measured in 40 nonsmoker men, all free from medication and disease history, insubjects divided in two groups: 18-25 and 50-70 years old with mean age of 22±1.3 and 59±2 years respectively. Using a mercury-column sphygmomanometer (ERKA) with appropriate cuff size and after five minutes of quiet rest, the blood pressure was determined in supine posture at three separate times. The lower limb pressure was measured with placing the cuff on calf muscle and the stethoscope on posterior surface of internal malleolus. The mean of the second and third records rounded and were used for analysis. Results: The right and left brachial and ankles pulse pressure in two groups were: 44.50±2.03, 44.50±1.71, 37.90±2.24, 37.25±2.30 mmHg in 18-25 years old group and 47.10±2.74, 46.90±2.65, 56.05±3.18, 55.90±4.48 mmHg in 50-70 years old group, respectively. Significant differences were found between brachial and ankle pulse pressure in both sides in first group, (P<0.05). In the second group this difference was only significant at right, (P<0.05). The ratio of brachial pulse pressure to ankle pulse pressure in 18-25 years old group was greater than 1 and in 50-70 years old group it was less than .15 In both side the ankles pulse pressure was significantly greater in 50-70 years old group (P<0.05). Conclusion: This study showed that in subjects of more than 55 years of age, the increasing of pulse pressure was more prominent in lower limb. The ankle pulse pressure may be a proper index of central pulse pressure changes and atherosclerosis of elastic arteries with ageing.
first_indexed 2024-04-13T02:56:35Z
format Article
id doaj.art-2c987c6025154a458bbad45c495dbf0e
institution Directory Open Access Journal
issn 1562-4765
2008-4080
language fas
last_indexed 2024-04-13T02:56:35Z
publishDate 2009-05-01
publisher Golestan University of Medical Sciences
record_format Article
series مجله دانشگاه علوم پزشکی گرگان
spelling doaj.art-2c987c6025154a458bbad45c495dbf0e2022-12-22T03:05:36ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802009-05-011116770The relation between ageing and increasing pulse pressure in upper and lower limbsSeyed Mehran Hosseini (MD, PhD)0Ali Reza Maleki1 Background & Objective: Pulse pressure is a marker of arterial stiffness. In old age the pressure wave reflection also contribute to disparity of pulse pressure between upper and lower limbs. This study was done to determine the relation between ageing and increased pulse pressure of upper and lower limbs. Materials & Methods: In this discriptive study blood pressure measured in 40 nonsmoker men, all free from medication and disease history, insubjects divided in two groups: 18-25 and 50-70 years old with mean age of 22±1.3 and 59±2 years respectively. Using a mercury-column sphygmomanometer (ERKA) with appropriate cuff size and after five minutes of quiet rest, the blood pressure was determined in supine posture at three separate times. The lower limb pressure was measured with placing the cuff on calf muscle and the stethoscope on posterior surface of internal malleolus. The mean of the second and third records rounded and were used for analysis. Results: The right and left brachial and ankles pulse pressure in two groups were: 44.50±2.03, 44.50±1.71, 37.90±2.24, 37.25±2.30 mmHg in 18-25 years old group and 47.10±2.74, 46.90±2.65, 56.05±3.18, 55.90±4.48 mmHg in 50-70 years old group, respectively. Significant differences were found between brachial and ankle pulse pressure in both sides in first group, (P<0.05). In the second group this difference was only significant at right, (P<0.05). The ratio of brachial pulse pressure to ankle pulse pressure in 18-25 years old group was greater than 1 and in 50-70 years old group it was less than .15 In both side the ankles pulse pressure was significantly greater in 50-70 years old group (P<0.05). Conclusion: This study showed that in subjects of more than 55 years of age, the increasing of pulse pressure was more prominent in lower limb. The ankle pulse pressure may be a proper index of central pulse pressure changes and atherosclerosis of elastic arteries with ageing.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-349&slc_lang=en&sid=1Pulse pressureAgeingAnkle
spellingShingle Seyed Mehran Hosseini (MD, PhD)
Ali Reza Maleki
The relation between ageing and increasing pulse pressure in upper and lower limbs
مجله دانشگاه علوم پزشکی گرگان
Pulse pressure
Ageing
Ankle
title The relation between ageing and increasing pulse pressure in upper and lower limbs
title_full The relation between ageing and increasing pulse pressure in upper and lower limbs
title_fullStr The relation between ageing and increasing pulse pressure in upper and lower limbs
title_full_unstemmed The relation between ageing and increasing pulse pressure in upper and lower limbs
title_short The relation between ageing and increasing pulse pressure in upper and lower limbs
title_sort relation between ageing and increasing pulse pressure in upper and lower limbs
topic Pulse pressure
Ageing
Ankle
url http://goums.ac.ir/journal/browse.php?a_code=A-10-1-349&slc_lang=en&sid=1
work_keys_str_mv AT seyedmehranhosseinimdphd therelationbetweenageingandincreasingpulsepressureinupperandlowerlimbs
AT alirezamaleki therelationbetweenageingandincreasingpulsepressureinupperandlowerlimbs
AT seyedmehranhosseinimdphd relationbetweenageingandincreasingpulsepressureinupperandlowerlimbs
AT alirezamaleki relationbetweenageingandincreasingpulsepressureinupperandlowerlimbs