A single N-terminal amino acid determines the distinct roles of histones H3 and H3.3 in the Drosophila male germline stem cell lineage.

Adult stem cells undergo asymmetric cell divisions to produce 2 daughter cells with distinct cell fates: one capable of self-renewal and the other committed for differentiation. Misregulation of this delicate balance can lead to cancer and tissue degeneration. During asymmetric division of Drosophil...

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Bibliographic Details
Main Authors: Chinmayi Chandrasekhara, Rajesh Ranjan, Jennifer A Urban, Brendon E M Davis, Wai Lim Ku, Jonathan Snedeker, Keji Zhao, Xin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-05-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3002098

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