Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment

Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment

Apolipoprotein E (apoE) occurs on the majority of plasma lipoproteins and plays a major role in the lipid metabolism in the periphery and in the central nervous system. ApoE is a polymorphic protein with three common isoforms, apoE2, apoE3 and apoE4, derived from respective alleles ε2, ε3 and ε4. Th...

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Bibliographic Details
Main Authors: Ilijana Begcevic Brkovic, Benedikt Zöhrer, Markus Scholz, Madlen Reinicke, Julia Dittrich, Surab Kamalsada, Ronny Baber, Frank Beutner, Andrej Teren, Christoph Engel, Kerstin Wirkner, Holger Thiele, Markus Löffler, Steffi G. Riedel-Heller, Uta Ceglarek
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Nutrients
Subjects:
apolipoproteins
apolipoprotein E phenotype
liquid chromatography
mass spectrometry
proteomics
Online Access:https://www.mdpi.com/2072-6643/14/12/2474

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