Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance
Hepatic steatosis is associated with poor cardiometabolic health, with de novo lipogenesis (DNL) contributing to hepatic steatosis and subsequent insulin resistance. Here, the authors use 1H-MRS methodology to show hepatic SFA fraction is a measure of DNL and specifically may hamper hepatic insulin...
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Bibliographic Details
| Main Authors: |
Kay H. M. Roumans,
Lucas Lindeboom,
Pandichelvam Veeraiah,
Carlijn M. E. Remie,
Esther Phielix,
Bas Havekes,
Yvonne M. H. Bruls,
Martijn C. G. J. Brouwers,
Marcus Ståhlman,
Marjan Alssema,
Harry P. F. Peters,
Renée de Mutsert,
Bart Staels,
Marja-Riitta Taskinen,
Jan Borén,
Patrick Schrauwen,
Vera B. Schrauwen-Hinderling |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-15684-0
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