Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey
Introduction: Transfusion-related infections are usually caused by a microbial pathogen transmitted to the recipient by the donated blood. Plasmodium spp., Trypanosoma cruzi, Babesia microti, Toxoplasma gondii and Leishmania spp. are listed as the most widely reported transfusion-transmitted parasit...
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| Format: | Article |
| Language: | English |
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Bilimsel Tip Yayinevi
2020-03-01
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| Series: | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2020-25-01-033-039.pdf |
| _version_ | 1797922584916918272 |
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| author | Gül BAYRAM Ender DİNÇER Sema ERDEN ERTÜRK Eyüp Naci TİFTİK |
| author_facet | Gül BAYRAM Ender DİNÇER Sema ERDEN ERTÜRK Eyüp Naci TİFTİK |
| author_sort | Gül BAYRAM |
| collection | DOAJ |
| description | Introduction: Transfusion-related infections are usually caused by a microbial pathogen transmitted to the recipient by the donated blood. Plasmodium spp., Trypanosoma cruzi, Babesia microti, Toxoplasma gondii and Leishmania spp. are listed as the most widely reported transfusion-transmitted parasites. Leishmaniasis is well known as an endemic in Mediterranean countries including Turkey. Accordingly, detection of asymptomatic Leishmania infantum carriage in blood donors is an important issue in Turkey. In endemic teretories, research on blood donors is under-represented in Turkey. Likewise, Mersin province is also endemic for Leishmaniasis. Up to date, no studies have been conducted to detect Leishmaniasis in healthy blood donors in our region. Therefore, the main objective of the current study was to reveal the seroprevalance of asymptomatic Leishmania carriage among the blood donors in Mersin province.
Materials and Methods: A total of 509 blood samples were collected from blood donors during a 12-month period between June 2016 and June 2017 at Mersin University Health Research and Application Center. Collected questionnaires were evaluated to determine the risk of exposure to Leishmania spp. Serological and molecular methods were assesed on the collected blood specimens.
Results: Based on the questionnaires, a total number of 509 donors participated the study, living in the city center (n= 367), district (n= 121), town (n= 7) and village (n= 14) respectively. A veterinarian and a sailor as well as 17 farmers were listed in the risky occupational groups. The number of dog and cat owner donors were reported as 41 and 20, respectively. All samples were found to be negative for Leishmania spp. by ELISA and real-time polymerase chain reaction methods.
Conclusion: This research is the first to assess Leishmaniasis risk in Mersin province. It is highly recommended not to utilize Leishmania spp. screening into the routine test packages in blood banks in our region. |
| first_indexed | 2024-04-10T14:34:44Z |
| format | Article |
| id | doaj.art-2c9c7ea4b82545fc8e6d9367e15ac027 |
| institution | Directory Open Access Journal |
| issn | 1300-932X 1308-5115 |
| language | English |
| last_indexed | 2024-04-10T14:34:44Z |
| publishDate | 2020-03-01 |
| publisher | Bilimsel Tip Yayinevi |
| record_format | Article |
| series | Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi |
| spelling | doaj.art-2c9c7ea4b82545fc8e6d9367e15ac0272023-02-15T16:08:40ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1308-51152020-03-01251333910.5578/flora.68443Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in TurkeyGül BAYRAM0https://orcid.org/0000-0002-4154-8596Ender DİNÇER1https://orcid.org/0000-0003-2885-8415Sema ERDEN ERTÜRK2https://orcid.org/0000-0002-1988-8674Eyüp Naci TİFTİK3https://orcid.org/0000-0002-9009-7066Medical Laboratory Techniques, Department of Medical Services and Techniques, University of Mersin Health Services Vocational School, Mersin, TurkeyUniversity of Mersin Advanced Technology Education Research and Application Center, Mersin, TurkeyUniversity of Mersin Health Services Vocational School, Mersin, TurkeyDepartment of Internal Medicine, Faculty of Medicine, University of Mersin, Mersin, TurkeyIntroduction: Transfusion-related infections are usually caused by a microbial pathogen transmitted to the recipient by the donated blood. Plasmodium spp., Trypanosoma cruzi, Babesia microti, Toxoplasma gondii and Leishmania spp. are listed as the most widely reported transfusion-transmitted parasites. Leishmaniasis is well known as an endemic in Mediterranean countries including Turkey. Accordingly, detection of asymptomatic Leishmania infantum carriage in blood donors is an important issue in Turkey. In endemic teretories, research on blood donors is under-represented in Turkey. Likewise, Mersin province is also endemic for Leishmaniasis. Up to date, no studies have been conducted to detect Leishmaniasis in healthy blood donors in our region. Therefore, the main objective of the current study was to reveal the seroprevalance of asymptomatic Leishmania carriage among the blood donors in Mersin province. Materials and Methods: A total of 509 blood samples were collected from blood donors during a 12-month period between June 2016 and June 2017 at Mersin University Health Research and Application Center. Collected questionnaires were evaluated to determine the risk of exposure to Leishmania spp. Serological and molecular methods were assesed on the collected blood specimens. Results: Based on the questionnaires, a total number of 509 donors participated the study, living in the city center (n= 367), district (n= 121), town (n= 7) and village (n= 14) respectively. A veterinarian and a sailor as well as 17 farmers were listed in the risky occupational groups. The number of dog and cat owner donors were reported as 41 and 20, respectively. All samples were found to be negative for Leishmania spp. by ELISA and real-time polymerase chain reaction methods. Conclusion: This research is the first to assess Leishmaniasis risk in Mersin province. It is highly recommended not to utilize Leishmania spp. screening into the routine test packages in blood banks in our region.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2020-25-01-033-039.pdftransfusion-related infectionblood donorendemicleishmania spp. |
| spellingShingle | Gül BAYRAM Ender DİNÇER Sema ERDEN ERTÜRK Eyüp Naci TİFTİK Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi transfusion-related infection blood donor endemic leishmania spp. |
| title | Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey |
| title_full | Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey |
| title_fullStr | Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey |
| title_full_unstemmed | Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey |
| title_short | Seroprevalence of Asymptomatic Leishmania spp. Carriage Among Blood Donors in Leishmaniasis Endemic Area in Turkey |
| title_sort | seroprevalence of asymptomatic leishmania spp carriage among blood donors in leishmaniasis endemic area in turkey |
| topic | transfusion-related infection blood donor endemic leishmania spp. |
| url | http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2020-25-01-033-039.pdf |
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