The role of RAGE, MAPK and NF-κB pathway in the advanced glycation end-products induced HUVECs dysfunction

The role of RAGE, MAPK and NF-κB pathway in the advanced glycation end-products induced HUVECs dysfunction

OBJECTIVE: The objective of this study was to investigate how receptor for advanced glycation end-products–mitogen-activated protein kinase–nuclear factor-kappa B (MAPK-NF-κB) pathway is involved in advanced glycation end-product (AGE)-induced human umbilical venous endothelial cell (HUVEC) dysfunct...

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Bibliographic Details
Main Authors: Xun Wang, Yi-Shu Wang, Qing-Long Zeng, Chen-Yang Qiu, Yang-Yan He, Zi-Heng Wu, Yun-Jun He, Tao Shang, Hong-Kun Zhang, Qian-Qian Zhu, Dong-Lin Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Vascular Investigation and Therapy
Subjects:
advanced glycation end-products
endothelial dysfunction
mitogen-activated protein kinase
nuclear factor-kappa b
Online Access:http://www.vitonline.org/article.asp?issn=2589-9686;year=2022;volume=5;issue=3;spage=80;epage=87;aulast=Wang

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