Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth
Abstract Background High myopia with shallow anterior chamber depth (ACD less than 2.8 mm) is not rare. This observational study aims to evaluate visual outcomes after implantation of the Visian Implantable Collamer Lens with a central hole (ICL V4c) in these patients. Methods A prospective cohort o...
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12886-019-1132-z |
| _version_ | 1818483068796665856 |
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| author | Lingling Niu Huamao Miao Tian Han Lan Ding Xiaoying Wang Xingtao Zhou |
| author_facet | Lingling Niu Huamao Miao Tian Han Lan Ding Xiaoying Wang Xingtao Zhou |
| author_sort | Lingling Niu |
| collection | DOAJ |
| description | Abstract Background High myopia with shallow anterior chamber depth (ACD less than 2.8 mm) is not rare. This observational study aims to evaluate visual outcomes after implantation of the Visian Implantable Collamer Lens with a central hole (ICL V4c) in these patients. Methods A prospective cohort of consecutive 51 eyes of 31 patients (20 to 42 years old) was followed for at least 12 months (average 15.35 ± 4.90 months, rangers from 12 to 25 months). The preoperative ACD was 2.74 ± 0.04 mm (2.65 to 2.79 mm). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), intraocular pressure (IOP), manifest refraction, vault, and endothelial cell density (ECD) were measured during the follow-ups after surgery. Results All surgeries were performed safely and no complication was observed during the follow-ups. At the last follow-up, the safety index (postoperative CDVA / preoperative CDVA) was 1.33 ± 0.60 and the efficacy index (postoperative UDVA / preoperative CDVA) was 1.14 ± 0.54. After the surgery, no eye had decreased CDVA and 59% (30 eyes) of the eyes gained at least one line. Forty-seven eyes (92%) were within ±1.0 D and 35 eyes (69%) were within ±0.5 D of the attempted refraction. The mean postoperative vault was 380.00 ± 152.84 μm (90 to 700 μm). The ECD was reduced by 8.38 ± 0.06% as compared to the preoperative value (p < 0.001). No significant change was observed in IOP (p = 0.061) at the last follow-up. Ultrasound Biomicroscopy (UBM) showed none of the eyes had trabecular-iris angle closed. Conclusions In this prospective observational study, ICL V4c implantation in patients with high myopia and shallow ACD achieved satisfying and stable visual outcomes. Its long-term safety and stability require further investigation. Trial registration This trial was retrospectively registered on 05/08/2018 under the number (ChiCTR1800017594). |
| first_indexed | 2024-12-10T11:55:27Z |
| format | Article |
| id | doaj.art-2ca914f35a31488ea9ddd3658a7cc3bd |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-10T11:55:27Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-2ca914f35a31488ea9ddd3658a7cc3bd2022-12-22T01:49:47ZengBMCBMC Ophthalmology1471-24152019-05-011911610.1186/s12886-019-1132-zVisual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depthLingling Niu0Huamao Miao1Tian Han2Lan Ding3Xiaoying Wang4Xingtao Zhou5Department of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan UniversityDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan UniversityDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan UniversityDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan UniversityDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan UniversityDepartment of Ophthalmology and Optometry, Eye and ENT Hospital, Fudan UniversityAbstract Background High myopia with shallow anterior chamber depth (ACD less than 2.8 mm) is not rare. This observational study aims to evaluate visual outcomes after implantation of the Visian Implantable Collamer Lens with a central hole (ICL V4c) in these patients. Methods A prospective cohort of consecutive 51 eyes of 31 patients (20 to 42 years old) was followed for at least 12 months (average 15.35 ± 4.90 months, rangers from 12 to 25 months). The preoperative ACD was 2.74 ± 0.04 mm (2.65 to 2.79 mm). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), intraocular pressure (IOP), manifest refraction, vault, and endothelial cell density (ECD) were measured during the follow-ups after surgery. Results All surgeries were performed safely and no complication was observed during the follow-ups. At the last follow-up, the safety index (postoperative CDVA / preoperative CDVA) was 1.33 ± 0.60 and the efficacy index (postoperative UDVA / preoperative CDVA) was 1.14 ± 0.54. After the surgery, no eye had decreased CDVA and 59% (30 eyes) of the eyes gained at least one line. Forty-seven eyes (92%) were within ±1.0 D and 35 eyes (69%) were within ±0.5 D of the attempted refraction. The mean postoperative vault was 380.00 ± 152.84 μm (90 to 700 μm). The ECD was reduced by 8.38 ± 0.06% as compared to the preoperative value (p < 0.001). No significant change was observed in IOP (p = 0.061) at the last follow-up. Ultrasound Biomicroscopy (UBM) showed none of the eyes had trabecular-iris angle closed. Conclusions In this prospective observational study, ICL V4c implantation in patients with high myopia and shallow ACD achieved satisfying and stable visual outcomes. Its long-term safety and stability require further investigation. Trial registration This trial was retrospectively registered on 05/08/2018 under the number (ChiCTR1800017594).http://link.springer.com/article/10.1186/s12886-019-1132-zHigh myopiaICL V4cAnterior chamber depth |
| spellingShingle | Lingling Niu Huamao Miao Tian Han Lan Ding Xiaoying Wang Xingtao Zhou Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth BMC Ophthalmology High myopia ICL V4c Anterior chamber depth |
| title | Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth |
| title_full | Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth |
| title_fullStr | Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth |
| title_full_unstemmed | Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth |
| title_short | Visual outcomes of Visian ICL implantation for high myopia in patients with shallow anterior chamber depth |
| title_sort | visual outcomes of visian icl implantation for high myopia in patients with shallow anterior chamber depth |
| topic | High myopia ICL V4c Anterior chamber depth |
| url | http://link.springer.com/article/10.1186/s12886-019-1132-z |
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