A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases

BACKGROUND: The bone marrow is widely distributed organ and is the principle site for blood cells formation. The broad spectrum of disorders affects the marrow primarily or secondarily with presentation of peripheral pancytopenia. Hence, bone marrow examination is extremely helpful in evaluation of...

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Format: Article
Language:English
Published: Prathima Institute of Medical Sciences 2022-08-01
Series:Perspectives In Medical Research
Online Access:https://pimr.org.in/2022-vol10-issue-2/originalarticle8_v2.pdf
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collection DOAJ
description BACKGROUND: The bone marrow is widely distributed organ and is the principle site for blood cells formation. The broad spectrum of disorders affects the marrow primarily or secondarily with presentation of peripheral pancytopenia. Hence, bone marrow examination is extremely helpful in evaluation of pancytopenia. This study emphasizes the different causes of pancytopenia and bone marrow morphology in cases of pancytopenia. MATERIALS & METHODS: The present study is a retrospective and prospective study done in the department of Pathology, for a period of two years. All the relevant history, clinical details, radiological details, and biochemistry parameters were considered. RESULTS: Out of 150 cases,96 were males and 54 were females. Majority of the patients were in the age group of 41-60 years (54%) amongst whom Megaloblastic anaemia was the most important cause of pancytopenia. CONCLUSION: Bone marrow aspiration is relatively a very safe invasive procedure and primarily permits cytological assessment since the underlying pathology determines the management and prognosis of the patients.
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spelling doaj.art-2cada3ebd7374697a9c7f432a7962fc02023-11-24T11:52:42ZengPrathima Institute of Medical SciencesPerspectives In Medical Research2348-229X2022-08-011010.47799/pimr.1002.100010A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 CasesBACKGROUND: The bone marrow is widely distributed organ and is the principle site for blood cells formation. The broad spectrum of disorders affects the marrow primarily or secondarily with presentation of peripheral pancytopenia. Hence, bone marrow examination is extremely helpful in evaluation of pancytopenia. This study emphasizes the different causes of pancytopenia and bone marrow morphology in cases of pancytopenia. MATERIALS & METHODS: The present study is a retrospective and prospective study done in the department of Pathology, for a period of two years. All the relevant history, clinical details, radiological details, and biochemistry parameters were considered. RESULTS: Out of 150 cases,96 were males and 54 were females. Majority of the patients were in the age group of 41-60 years (54%) amongst whom Megaloblastic anaemia was the most important cause of pancytopenia. CONCLUSION: Bone marrow aspiration is relatively a very safe invasive procedure and primarily permits cytological assessment since the underlying pathology determines the management and prognosis of the patients.https://pimr.org.in/2022-vol10-issue-2/originalarticle8_v2.pdf
spellingShingle A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases
Perspectives In Medical Research
title A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases
title_full A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases
title_fullStr A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases
title_full_unstemmed A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases
title_short A Prospective and Retrospective Study of Bone Marrow in Patients with Pancytopenia– A Study of 150 Cases
title_sort prospective and retrospective study of bone marrow in patients with pancytopenia a study of 150 cases
url https://pimr.org.in/2022-vol10-issue-2/originalarticle8_v2.pdf