The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review
Abstract Background Depression is highly prevalent among Haemodialysis (HD) patients and is known to results in a series of adverse outcomes and poor quality of life (QoL). Although cognitive behavioural therapy (CBT) has been shown to improve depressive symptoms and QoL in other chronic illness, th...
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| Format: | Article |
| Language: | English |
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BMC
2020-07-01
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| Series: | BMC Psychiatry |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12888-020-02754-2 |
| _version_ | 1828157382343000064 |
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| author | Chen Ling Debra Evans Yunfang Zhang Jianying Luo Yanping Hu Yuxia Ouyang Jiamin Tang Ziqiao Kuang |
| author_facet | Chen Ling Debra Evans Yunfang Zhang Jianying Luo Yanping Hu Yuxia Ouyang Jiamin Tang Ziqiao Kuang |
| author_sort | Chen Ling |
| collection | DOAJ |
| description | Abstract Background Depression is highly prevalent among Haemodialysis (HD) patients and is known to results in a series of adverse outcomes and poor quality of life (QoL). Although cognitive behavioural therapy (CBT) has been shown to improve depressive symptoms and QoL in other chronic illness, there is uncertainty in terms of the effectiveness of CBT in HD patients with depression or depressive symptoms. Methods All randomised controlled trials relevant to the topic were retrieved from the following databases: CINHAL, MEDLINE, PubMed, PsycINFO and CENTRAL. The grey literature, specific journals, reference lists of included studies and trials registers website were also searched. Data was extracted or calculated from included studies that had measured depression and quality of life using valid and reliable tools –this included mean differences or standardised mean differences and 95% confidence intervals. The Cochrane risk of bias tool was used to identify the methodological quality of the included studies. Results Six RCTs were included with varying methodological quality. Meta-analysis was undertaken for 3 studies that employed the CBT versus usual care. All studies showed that the depressive symptoms significantly improved after the CBT. Furthermore, CBT was more effective than usual care (MD = − 5.28, 95%CI − 7.9 to − 2.65, P = 0.37) and counselling (MD = − 2.39, 95%CI − 3.49 to − 1.29), while less effective than sertraline (MD = 2.2, 95%CI 0.43 to 3.97) in alleviating depressive symptoms. Additionally, the CBT seems to have a beneficial effect in improving QoL when compared with usual care, while no significant difference was found in QoL score when compared CBT with sertraline. Conclusions CBT may improve depressive symptoms and QoL in HD patients with comorbid depressive symptoms. However, more rigorous studies are needed in this field due to the small quantity and varied methodological quality in the identified studies. |
| first_indexed | 2024-04-11T23:27:20Z |
| format | Article |
| id | doaj.art-2cb40dfa0f68487698c8282859ec32e8 |
| institution | Directory Open Access Journal |
| issn | 1471-244X |
| language | English |
| last_indexed | 2024-04-11T23:27:20Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj.art-2cb40dfa0f68487698c8282859ec32e82022-12-22T03:57:16ZengBMCBMC Psychiatry1471-244X2020-07-0120111410.1186/s12888-020-02754-2The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic reviewChen Ling0Debra Evans1Yunfang Zhang2Jianying Luo3Yanping Hu4Yuxia Ouyang5Jiamin Tang6Ziqiao Kuang7Department of Nephrology, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Birmingham City University, City South Campus, Faculty of Health, Education and Life SciencesDepartment of Nephrology, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Nursing Department, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Nursing Department, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Nursing Department, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Department of Nephrology, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Department of Breast Surgery, Huadu Hospital, Southern Medical University (People’s Hospital of Huadu District)Abstract Background Depression is highly prevalent among Haemodialysis (HD) patients and is known to results in a series of adverse outcomes and poor quality of life (QoL). Although cognitive behavioural therapy (CBT) has been shown to improve depressive symptoms and QoL in other chronic illness, there is uncertainty in terms of the effectiveness of CBT in HD patients with depression or depressive symptoms. Methods All randomised controlled trials relevant to the topic were retrieved from the following databases: CINHAL, MEDLINE, PubMed, PsycINFO and CENTRAL. The grey literature, specific journals, reference lists of included studies and trials registers website were also searched. Data was extracted or calculated from included studies that had measured depression and quality of life using valid and reliable tools –this included mean differences or standardised mean differences and 95% confidence intervals. The Cochrane risk of bias tool was used to identify the methodological quality of the included studies. Results Six RCTs were included with varying methodological quality. Meta-analysis was undertaken for 3 studies that employed the CBT versus usual care. All studies showed that the depressive symptoms significantly improved after the CBT. Furthermore, CBT was more effective than usual care (MD = − 5.28, 95%CI − 7.9 to − 2.65, P = 0.37) and counselling (MD = − 2.39, 95%CI − 3.49 to − 1.29), while less effective than sertraline (MD = 2.2, 95%CI 0.43 to 3.97) in alleviating depressive symptoms. Additionally, the CBT seems to have a beneficial effect in improving QoL when compared with usual care, while no significant difference was found in QoL score when compared CBT with sertraline. Conclusions CBT may improve depressive symptoms and QoL in HD patients with comorbid depressive symptoms. However, more rigorous studies are needed in this field due to the small quantity and varied methodological quality in the identified studies.http://link.springer.com/article/10.1186/s12888-020-02754-2HaemodialysisCognitive behavioural therapyDepressionQuality of life |
| spellingShingle | Chen Ling Debra Evans Yunfang Zhang Jianying Luo Yanping Hu Yuxia Ouyang Jiamin Tang Ziqiao Kuang The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review BMC Psychiatry Haemodialysis Cognitive behavioural therapy Depression Quality of life |
| title | The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review |
| title_full | The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review |
| title_fullStr | The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review |
| title_full_unstemmed | The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review |
| title_short | The effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis: a systematic review |
| title_sort | effects of cognitive behavioural therapy on depression and quality of life in patients with maintenance haemodialysis a systematic review |
| topic | Haemodialysis Cognitive behavioural therapy Depression Quality of life |
| url | http://link.springer.com/article/10.1186/s12888-020-02754-2 |
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