Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?

Background: Cardiac failure with preserved ejection fraction corresponds to half of the cardiac failure cases, having a similar prognosis to patients with reduced ejection fraction. Cardiac sudden death is responsible to about one quarter of the death on these patients. Despite some trials were int...

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Main Authors: Bruno Finkler, Tiago Luiz Luz Leiria, Clovis Fröemming Jr, Javier Pinos, Danilo Barros Zanotta, Marcelo Lapa Kruse, Leonardo Martins Pires, Gustavo Glotz de Lima
Format: Article
Language:English
Published: Linceu Editorial 2020-05-01
Series:Journal of Cardiac Arrhythmias
Subjects:
Online Access:https://jca.emnuvens.com.br/jca/article/view/3385
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author Bruno Finkler
Tiago Luiz Luz Leiria
Clovis Fröemming Jr
Javier Pinos
Danilo Barros Zanotta
Marcelo Lapa Kruse
Leonardo Martins Pires
Gustavo Glotz de Lima
author_facet Bruno Finkler
Tiago Luiz Luz Leiria
Clovis Fröemming Jr
Javier Pinos
Danilo Barros Zanotta
Marcelo Lapa Kruse
Leonardo Martins Pires
Gustavo Glotz de Lima
author_sort Bruno Finkler
collection DOAJ
description Background: Cardiac failure with preserved ejection fraction corresponds to half of the cardiac failure cases, having a similar prognosis to patients with reduced ejection fraction. Cardiac sudden death is responsible to about one quarter of the death on these patients. Despite some trials were intended to identify patients with a higher risk to these outcome, it is not already know: how we should proceed to stratify the risk of sudden death in this patients. Methods: To assess the profile of patients with cardiac sudden death and cardiac failure with preserved ejection fraction, we did a literature review, searching for the newer articles about the theme. Outcome: Several trials were published involving patients with divers characteristics that can help us to identify patients with a higher risk of sudden death. The publication of risk score demonstrated that would be possible to identify patients with a >10% risk of sudden death in 5 years, what would be equivalent to the risk of reduced ejection fraction patients eligible to implantable cardioverter-defibrillator (ICD) therapy. Trials with electrophysiological study and programmed ventricular stimulation showed a good strategy to identify low risk patients for future arrhythmic events. Conclusion: Sudden death must be a target of the therapy in the patients with preserved heart failure. Efforts should be done with the objective to identify higher risk patients and search for the better risk stratification strategy, and after that, the definition of the benefit or not, of the invasive therapy as ICD. Keywords: Sudden Death; Cardiac Faillure; Preserved Ejection Fraction;
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spelling doaj.art-2cb4a10b3c9d4f58a7f9558aa99d36e12022-12-22T01:30:41ZengLinceu EditorialJournal of Cardiac Arrhythmias2674-74722020-05-01331Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?Bruno Finkler0Tiago Luiz Luz Leiria1Clovis Fröemming Jr2Javier Pinos3Danilo Barros Zanotta4Marcelo Lapa Kruse5Leonardo Martins Pires6Gustavo Glotz de Lima7Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil.Fundação Universitária de Cardiologia – Instituto de Cardiologia – Porto Alegre (RS), Brazil. Background: Cardiac failure with preserved ejection fraction corresponds to half of the cardiac failure cases, having a similar prognosis to patients with reduced ejection fraction. Cardiac sudden death is responsible to about one quarter of the death on these patients. Despite some trials were intended to identify patients with a higher risk to these outcome, it is not already know: how we should proceed to stratify the risk of sudden death in this patients. Methods: To assess the profile of patients with cardiac sudden death and cardiac failure with preserved ejection fraction, we did a literature review, searching for the newer articles about the theme. Outcome: Several trials were published involving patients with divers characteristics that can help us to identify patients with a higher risk of sudden death. The publication of risk score demonstrated that would be possible to identify patients with a >10% risk of sudden death in 5 years, what would be equivalent to the risk of reduced ejection fraction patients eligible to implantable cardioverter-defibrillator (ICD) therapy. Trials with electrophysiological study and programmed ventricular stimulation showed a good strategy to identify low risk patients for future arrhythmic events. Conclusion: Sudden death must be a target of the therapy in the patients with preserved heart failure. Efforts should be done with the objective to identify higher risk patients and search for the better risk stratification strategy, and after that, the definition of the benefit or not, of the invasive therapy as ICD. Keywords: Sudden Death; Cardiac Faillure; Preserved Ejection Fraction; https://jca.emnuvens.com.br/jca/article/view/3385Sudden deathCardiac failurePreserved ejection fraction
spellingShingle Bruno Finkler
Tiago Luiz Luz Leiria
Clovis Fröemming Jr
Javier Pinos
Danilo Barros Zanotta
Marcelo Lapa Kruse
Leonardo Martins Pires
Gustavo Glotz de Lima
Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?
Journal of Cardiac Arrhythmias
Sudden death
Cardiac failure
Preserved ejection fraction
title Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?
title_full Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?
title_fullStr Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?
title_full_unstemmed Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?
title_short Heart Failure with Preserved Ejection Fraction and Sudden Death: How to Identify High Risk Patients?
title_sort heart failure with preserved ejection fraction and sudden death how to identify high risk patients
topic Sudden death
Cardiac failure
Preserved ejection fraction
url https://jca.emnuvens.com.br/jca/article/view/3385
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