Progress in molecular mechanism and targeted drugs of bone metastases in breast cancer
Breast cancer is the most common malignant tumor that threatens the health of women around the world, and bone is the site most prone to metastasis. The molecular mechanism concerned and targeted therapy against bone metastasis of breast cancer have become the current research hotspots. This article...
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| Format: | Article |
| Language: | zho |
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Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College.
2021-03-01
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| Series: | Jichu yixue yu linchuang |
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| Online Access: | http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a200406.pdf |
| Summary: | Breast cancer is the most common malignant tumor that threatens the health of women around the world, and bone is the site most prone to metastasis. The molecular mechanism concerned and targeted therapy against bone metastasis of breast cancer have become the current research hotspots. This article summarizes the key molecules involved in regulating bone metastasis of breast cancer. The important targeted therapy drugs are introduced and their efficacy is compared in two categories of those targeting at osteoclasts and those targeting at osteoblasts. |
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| ISSN: | 1001-6325 |