<i>ZSCAN4</i> Regulates Zygotic Genome Activation and Telomere Elongation in Porcine Parthenogenetic Embryos

<i>ZSCAN4</i> Regulates Zygotic Genome Activation and Telomere Elongation in Porcine Parthenogenetic Embryos

Zinc finger and SCAN domain-containing 4 (<i>ZSCAN4</i>), a DNA-binding protein, maintains telomere length and plays a key role in critical aspects of mouse embryonic stem cells, including maintaining genomic stability and defying cellular senescence. However, the effect of <i>ZSCA...

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Bibliographic Details
Main Authors: Xiao-Han Li, Ming-Hong Sun, Wen-Jie Jiang, Dongjie Zhou, Song-Hee Lee, Geun Heo, Zhi Chen, Xiang-Shun Cui
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
<i>ZSCAN4</i>
<i>DNMT1</i>
DNA methylation
telomere length
ZGA
porcine embryos
Online Access:https://www.mdpi.com/1422-0067/24/15/12121

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