The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles

The characterization of nanoparticles is crucial in several medical applications, such as hyperthermic therapy, which heats superparamagnetic nanoparticles with an external electromagnetic field. The knowledge of heating ability (magnetic losses) in AC magnetic field frequency function allows for se...

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Main Authors: Mateusz Midura, Przemysław Wróblewski, Damian Wanta, Jacek Kryszyn, Waldemar T. Smolik, Grzegorz Domański, Michał Wieteska, Wojciech Obrębski, Ewa Piątkowska-Janko, Piotr Bogorodzki
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/22/8879
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author Mateusz Midura
Przemysław Wróblewski
Damian Wanta
Jacek Kryszyn
Waldemar T. Smolik
Grzegorz Domański
Michał Wieteska
Wojciech Obrębski
Ewa Piątkowska-Janko
Piotr Bogorodzki
author_facet Mateusz Midura
Przemysław Wróblewski
Damian Wanta
Jacek Kryszyn
Waldemar T. Smolik
Grzegorz Domański
Michał Wieteska
Wojciech Obrębski
Ewa Piątkowska-Janko
Piotr Bogorodzki
author_sort Mateusz Midura
collection DOAJ
description The characterization of nanoparticles is crucial in several medical applications, such as hyperthermic therapy, which heats superparamagnetic nanoparticles with an external electromagnetic field. The knowledge of heating ability (magnetic losses) in AC magnetic field frequency function allows for selecting the optimal excitation. A hybrid system for the characterization of superparamagnetic nanoparticles was designed and tested. The proposed setup consists of an excitation coil and two sensing probes: calorimetric and magnetic. The measurements of the imaginary part of the complex magnetic susceptibility of superparamagnetic nanoparticles are possible in the kilohertz range. The system was verified using a set of nanoparticles with different diameters. The measurement procedure was described and verified. The results confirmed that an elaborated sensor system and measuring procedures could properly characterize the magnetic characteristics of nanoparticles. The main advantage of this system is the ability to compare both characteristics and confirm the selection of optimal excitation parameters.
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spelling doaj.art-2cbbb9bdfdf04aa781df3cfa939976122023-11-24T09:57:15ZengMDPI AGSensors1424-82202022-11-012222887910.3390/s22228879The Hybrid System for the Magnetic Characterization of Superparamagnetic NanoparticlesMateusz Midura0Przemysław Wróblewski1Damian Wanta2Jacek Kryszyn3Waldemar T. Smolik4Grzegorz Domański5Michał Wieteska6Wojciech Obrębski7Ewa Piątkowska-Janko8Piotr Bogorodzki9Institute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandInstitute of Radioelectronics and Multimedia Technology, Warsaw University of Technology, 00-655 Warsaw, PolandThe characterization of nanoparticles is crucial in several medical applications, such as hyperthermic therapy, which heats superparamagnetic nanoparticles with an external electromagnetic field. The knowledge of heating ability (magnetic losses) in AC magnetic field frequency function allows for selecting the optimal excitation. A hybrid system for the characterization of superparamagnetic nanoparticles was designed and tested. The proposed setup consists of an excitation coil and two sensing probes: calorimetric and magnetic. The measurements of the imaginary part of the complex magnetic susceptibility of superparamagnetic nanoparticles are possible in the kilohertz range. The system was verified using a set of nanoparticles with different diameters. The measurement procedure was described and verified. The results confirmed that an elaborated sensor system and measuring procedures could properly characterize the magnetic characteristics of nanoparticles. The main advantage of this system is the ability to compare both characteristics and confirm the selection of optimal excitation parameters.https://www.mdpi.com/1424-8220/22/22/8879complex magnetic susceptibilitysuperparamagnetic nanoparticlesAC magnetometryhyperthermia therapy
spellingShingle Mateusz Midura
Przemysław Wróblewski
Damian Wanta
Jacek Kryszyn
Waldemar T. Smolik
Grzegorz Domański
Michał Wieteska
Wojciech Obrębski
Ewa Piątkowska-Janko
Piotr Bogorodzki
The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles
Sensors
complex magnetic susceptibility
superparamagnetic nanoparticles
AC magnetometry
hyperthermia therapy
title The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles
title_full The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles
title_fullStr The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles
title_full_unstemmed The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles
title_short The Hybrid System for the Magnetic Characterization of Superparamagnetic Nanoparticles
title_sort hybrid system for the magnetic characterization of superparamagnetic nanoparticles
topic complex magnetic susceptibility
superparamagnetic nanoparticles
AC magnetometry
hyperthermia therapy
url https://www.mdpi.com/1424-8220/22/22/8879
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