The double‐edged sword of endoplasmic reticulum stress in uremic sarcopenia through myogenesis perturbation
Abstract Background Sarcopenia is the age‐related degeneration characterized with the decline of skeletal muscle mass, strength, and function. The imbalance of protein synthesis and degradation which jeopardizes immune, hormone regulation, and muscle‐motor neuron connection is the main cause of sarc...
Main Authors: | Jia‐Rong Jheng, Yuan‐Siao Chen, Un Iong Ao, Ding‐Cheng Chan, Jenq‐Wen Huang, Kuang‐Yu Hung, Der‐Cheng Tarng, Chih‐Kang Chiang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-06-01
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Series: | Journal of Cachexia, Sarcopenia and Muscle |
Subjects: | |
Online Access: | https://doi.org/10.1002/jcsm.12288 |
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