Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review
Abstract Background Multifocal epithelial hyperplasia (MEH), or focal epithelial hypertension (FEH), or Heck’s disease, is an uncommon, benign oral mucosal disease associated with human papillomavirus infection. It is mostly observed in indigenous populations of the world, and has been rarely report...
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| Format: | Article |
| Language: | English |
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BMC
2023-09-01
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| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12903-023-03282-7 |
| _version_ | 1797451253655011328 |
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| author | Qianting Wang Lehan Xu Xiaojun Li Mengfei Yu Qianming Chen |
| author_facet | Qianting Wang Lehan Xu Xiaojun Li Mengfei Yu Qianming Chen |
| author_sort | Qianting Wang |
| collection | DOAJ |
| description | Abstract Background Multifocal epithelial hyperplasia (MEH), or focal epithelial hypertension (FEH), or Heck’s disease, is an uncommon, benign oral mucosal disease associated with human papillomavirus infection. It is mostly observed in indigenous populations of the world, and has been rarely reported in China. However, previous research suggested there might be a greater prevalence of MEH in the Chinese population. While predominantly involves the lips, buccal mucosa and tongue, MEH was occasionally reported to affect the hard palate and gingiva as well. Case presentation This paper reports a case of extensive MEH lesions that confined to the interdental papilla of a Chinese male without detection of HPV, and summarizes the published gingiva-involved MEH reports from 1966 until present. The lesions were excised with an Er: YAG laser after scaling and root planning, no recurrence was observed after 6-month follow-up. Conclusions The present report illustrates the need for clinicians to be aware of rare presentations of MEH to facilitate a prompt diagnosis and proper management. More reports are encouraged to determine a correct prevalence rate of MEH in China. |
| first_indexed | 2024-03-09T14:52:02Z |
| format | Article |
| id | doaj.art-2cbcdd126a0f4307808a86205317117a |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-03-09T14:52:02Z |
| publishDate | 2023-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-2cbcdd126a0f4307808a86205317117a2023-11-26T14:24:10ZengBMCBMC Oral Health1472-68312023-09-012311810.1186/s12903-023-03282-7Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature reviewQianting Wang0Lehan Xu1Xiaojun Li2Mengfei Yu3Qianming Chen4Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang UniversityStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang UniversityStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang UniversityStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang UniversityStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang UniversityAbstract Background Multifocal epithelial hyperplasia (MEH), or focal epithelial hypertension (FEH), or Heck’s disease, is an uncommon, benign oral mucosal disease associated with human papillomavirus infection. It is mostly observed in indigenous populations of the world, and has been rarely reported in China. However, previous research suggested there might be a greater prevalence of MEH in the Chinese population. While predominantly involves the lips, buccal mucosa and tongue, MEH was occasionally reported to affect the hard palate and gingiva as well. Case presentation This paper reports a case of extensive MEH lesions that confined to the interdental papilla of a Chinese male without detection of HPV, and summarizes the published gingiva-involved MEH reports from 1966 until present. The lesions were excised with an Er: YAG laser after scaling and root planning, no recurrence was observed after 6-month follow-up. Conclusions The present report illustrates the need for clinicians to be aware of rare presentations of MEH to facilitate a prompt diagnosis and proper management. More reports are encouraged to determine a correct prevalence rate of MEH in China.https://doi.org/10.1186/s12903-023-03282-7Multifocal epithelial hyperplasiaHeck’s diseaseHuman papillomavirusGingivaCase report |
| spellingShingle | Qianting Wang Lehan Xu Xiaojun Li Mengfei Yu Qianming Chen Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review BMC Oral Health Multifocal epithelial hyperplasia Heck’s disease Human papillomavirus Gingiva Case report |
| title | Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review |
| title_full | Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review |
| title_fullStr | Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review |
| title_full_unstemmed | Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review |
| title_short | Multifocal epithelial hyperplasia confined to the interdental papilla of an adult Chinese man: a rare case report and literature review |
| title_sort | multifocal epithelial hyperplasia confined to the interdental papilla of an adult chinese man a rare case report and literature review |
| topic | Multifocal epithelial hyperplasia Heck’s disease Human papillomavirus Gingiva Case report |
| url | https://doi.org/10.1186/s12903-023-03282-7 |
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