Genus Rubia: Therapeutic Effects and Toxicity: A Review
The Rubiaceae family taxonomic classification is complex. Genus Rubia with 70 species belongs to Rubieae tribe of Rubioideae subfamily of the Rubiaceae family. These species have been widely distributed and cultivated around the world, and are mainly concentrated in the tropics. The effects of bioa...
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| Format: | Article |
| Language: | English |
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Lorestan University of Medical Sciences
2022-08-01
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| Series: | Herbal Medicines Journal |
| Subjects: | |
| Online Access: | http://hmj.lums.ac.ir/index.php/hmj/article/view/903 |
| _version_ | 1811341713016356864 |
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| author | Marzieh Eskandarzadeh Akam Esmaeili Mohammad Reza Nikbakht Yukio Hitotsuyanagi Yuri N Shkryl Javad Ghasemian Yadegari Hassan Rezazadeh Javad Khalilifard * |
| author_facet | Marzieh Eskandarzadeh Akam Esmaeili Mohammad Reza Nikbakht Yukio Hitotsuyanagi Yuri N Shkryl Javad Ghasemian Yadegari Hassan Rezazadeh Javad Khalilifard * |
| author_sort | Marzieh Eskandarzadeh |
| collection | DOAJ |
| description |
The Rubiaceae family taxonomic classification is complex. Genus Rubia with 70 species belongs to Rubieae tribe of Rubioideae subfamily of the Rubiaceae family. These species have been widely distributed and cultivated around the world, and are mainly concentrated in the tropics. The effects of bioactive metabolites of various parts, particularly roots of Rubia species have been thoroughly examined, and their pharmacological and toxicological effects have been described. Antioxidant, anti-inflammatory, antitumor, antidiabetic, anti-arthritic, antiseizure and antimicrobial effects as well as toxicological properties of Rubia species have been previously reported. This study was conducted as a literature survey of various species of Rubiaceae published from 1992 to 2020. Moreover, their toxic and protective effects on living organisms were summarized.
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| first_indexed | 2024-04-13T18:58:01Z |
| format | Article |
| id | doaj.art-2cbeb8ecedde43b9a1388b9609db1ff3 |
| institution | Directory Open Access Journal |
| issn | 2538-2144 |
| language | English |
| last_indexed | 2024-04-13T18:58:01Z |
| publishDate | 2022-08-01 |
| publisher | Lorestan University of Medical Sciences |
| record_format | Article |
| series | Herbal Medicines Journal |
| spelling | doaj.art-2cbeb8ecedde43b9a1388b9609db1ff32022-12-22T02:34:10ZengLorestan University of Medical SciencesHerbal Medicines Journal2538-21442022-08-018110.22087/hmj.v8i1.903Genus Rubia: Therapeutic Effects and Toxicity: A ReviewMarzieh Eskandarzadeh0Akam Esmaeili1Mohammad Reza Nikbakht2Yukio Hitotsuyanagi3Yuri N Shkryl4Javad Ghasemian Yadegari5Hassan Rezazadeh6Javad Khalilifard *7Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, IranDepartment of Physiology and Pharmacology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hajiochi, Tokyo 192-03, Japan Federal Scientific Centre of the East Asia Terrestrial Biodiversity, Far Eastern Branch of Russian Academy of Sciences, Vladivostok, 690022, Russian FederationDepartment of Pharmacognosy, School of Pharmacy, Lorestan University of Medical Sciences, Khorramabad, IranDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, IranDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran The Rubiaceae family taxonomic classification is complex. Genus Rubia with 70 species belongs to Rubieae tribe of Rubioideae subfamily of the Rubiaceae family. These species have been widely distributed and cultivated around the world, and are mainly concentrated in the tropics. The effects of bioactive metabolites of various parts, particularly roots of Rubia species have been thoroughly examined, and their pharmacological and toxicological effects have been described. Antioxidant, anti-inflammatory, antitumor, antidiabetic, anti-arthritic, antiseizure and antimicrobial effects as well as toxicological properties of Rubia species have been previously reported. This study was conducted as a literature survey of various species of Rubiaceae published from 1992 to 2020. Moreover, their toxic and protective effects on living organisms were summarized. http://hmj.lums.ac.ir/index.php/hmj/article/view/903Rubiaceae, Rubieae, Rubia, Toxicity, Protective effects |
| spellingShingle | Marzieh Eskandarzadeh Akam Esmaeili Mohammad Reza Nikbakht Yukio Hitotsuyanagi Yuri N Shkryl Javad Ghasemian Yadegari Hassan Rezazadeh Javad Khalilifard * Genus Rubia: Therapeutic Effects and Toxicity: A Review Herbal Medicines Journal Rubiaceae, Rubieae, Rubia, Toxicity, Protective effects |
| title | Genus Rubia: Therapeutic Effects and Toxicity: A Review |
| title_full | Genus Rubia: Therapeutic Effects and Toxicity: A Review |
| title_fullStr | Genus Rubia: Therapeutic Effects and Toxicity: A Review |
| title_full_unstemmed | Genus Rubia: Therapeutic Effects and Toxicity: A Review |
| title_short | Genus Rubia: Therapeutic Effects and Toxicity: A Review |
| title_sort | genus rubia therapeutic effects and toxicity a review |
| topic | Rubiaceae, Rubieae, Rubia, Toxicity, Protective effects |
| url | http://hmj.lums.ac.ir/index.php/hmj/article/view/903 |
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