Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island
(1) Background: The prevalence of Spondyloarthritis (SpA) varies significantly in different regions and ethnic groups due several factors such as heterogeneity in study populations, the diversity of classification criteria used in epidemiological studies, the prevalence variability of HLA-B27 or dis...
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MDPI AG
2022-02-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/5/1299 |
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| author | Fabienne Louis-Sidney Valentine Kahn Benoit Suzon Michel De Bandt Christophe Deligny Serge Arfi Georges Jean-Baptiste |
| author_facet | Fabienne Louis-Sidney Valentine Kahn Benoit Suzon Michel De Bandt Christophe Deligny Serge Arfi Georges Jean-Baptiste |
| author_sort | Fabienne Louis-Sidney |
| collection | DOAJ |
| description | (1) Background: The prevalence of Spondyloarthritis (SpA) varies significantly in different regions and ethnic groups due several factors such as heterogeneity in study populations, the diversity of classification criteria used in epidemiological studies, the prevalence variability of HLA-B27 or disparity in healthcare access. To our knowledge, there is no data on SpA in Martinique, a French region in the Caribbean with a predominantly Afro-descendant population and a high level of healthcare. (2) Methods: This was a retrospective study of all SpA patients treated at the Fort de France University Hospital between 1 January 1997 and 1 January 2008. (3) Results: In our cohort of 86 SpA patients, age at diagnosis was late (41 years old), ankylosing spondylitis (AS) was the most frequent sub-type (60.5%), inflammatory bowel disease was the most frequent extra articular feature (23.3%) and no one had personal familial history of the disease. Inflammatory syndrome concerned 55.6% of patients, no one was positive for HIV and HLA-B27 positivity was low (42.2%). However, HLA-B27 was statistically associated with AS. Out of 64 patients, 41 had sacroiliitis. (4) Conclusion: To our knowledge, this is the first comprehensive descriptive study of SpA subtypes in Martinique, a French region in the Caribbean. We report clinical and biological similarities in our SpA cohort with those of sub-Saharan Africa and with SpA subtypes reported in Afro-descendant populations. |
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| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T20:34:45Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-2cbee04b8a684711a5f79c9b65281fde2023-11-23T23:13:48ZengMDPI AGJournal of Clinical Medicine2077-03832022-02-01115129910.3390/jcm11051299Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean IslandFabienne Louis-Sidney0Valentine Kahn1Benoit Suzon2Michel De Bandt3Christophe Deligny4Serge Arfi5Georges Jean-Baptiste6Service de Rhumatologie, CHU de Fort de France, 97200 Fort de France, Martinique, FranceService de Rhumatologie, CHU de Fort de France, 97200 Fort de France, Martinique, FranceService de Médecine Interne, CHU de Fort de France, 97200 Fort de France, Martinique, FranceService de Rhumatologie, CHU de Fort de France, 97200 Fort de France, Martinique, FranceService de Médecine Interne, CHU de Fort de France, 97200 Fort de France, Martinique, FranceService de Médecine Interne, CHU de Fort de France, 97200 Fort de France, Martinique, FranceService de Rhumatologie, CHU de Fort de France, 97200 Fort de France, Martinique, France(1) Background: The prevalence of Spondyloarthritis (SpA) varies significantly in different regions and ethnic groups due several factors such as heterogeneity in study populations, the diversity of classification criteria used in epidemiological studies, the prevalence variability of HLA-B27 or disparity in healthcare access. To our knowledge, there is no data on SpA in Martinique, a French region in the Caribbean with a predominantly Afro-descendant population and a high level of healthcare. (2) Methods: This was a retrospective study of all SpA patients treated at the Fort de France University Hospital between 1 January 1997 and 1 January 2008. (3) Results: In our cohort of 86 SpA patients, age at diagnosis was late (41 years old), ankylosing spondylitis (AS) was the most frequent sub-type (60.5%), inflammatory bowel disease was the most frequent extra articular feature (23.3%) and no one had personal familial history of the disease. Inflammatory syndrome concerned 55.6% of patients, no one was positive for HIV and HLA-B27 positivity was low (42.2%). However, HLA-B27 was statistically associated with AS. Out of 64 patients, 41 had sacroiliitis. (4) Conclusion: To our knowledge, this is the first comprehensive descriptive study of SpA subtypes in Martinique, a French region in the Caribbean. We report clinical and biological similarities in our SpA cohort with those of sub-Saharan Africa and with SpA subtypes reported in Afro-descendant populations.https://www.mdpi.com/2077-0383/11/5/1299spondyloarthritisepidemiologyMartiniquediagnosisHLA-B27 |
| spellingShingle | Fabienne Louis-Sidney Valentine Kahn Benoit Suzon Michel De Bandt Christophe Deligny Serge Arfi Georges Jean-Baptiste Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island Journal of Clinical Medicine spondyloarthritis epidemiology Martinique diagnosis HLA-B27 |
| title | Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island |
| title_full | Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island |
| title_fullStr | Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island |
| title_full_unstemmed | Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island |
| title_short | Epidemiology and Characteristics of Spondyloarthritis in the Predominantly Afro-Descendant Population of Martinique, a French Caribbean Island |
| title_sort | epidemiology and characteristics of spondyloarthritis in the predominantly afro descendant population of martinique a french caribbean island |
| topic | spondyloarthritis epidemiology Martinique diagnosis HLA-B27 |
| url | https://www.mdpi.com/2077-0383/11/5/1299 |
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