Successful treatment of multifocal cutaneous leishmaniasis with miltefosine
We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurat...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2011-01-01
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| Series: | Indian Journal of Dermatology |
| Subjects: | |
| Online Access: | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2011;volume=56;issue=5;spage=587;epage=590;aulast=Madke |
| _version_ | 1819242456649039872 |
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| author | Bhushan Madke Vidya Kharkar Siddhi Chikhalkar Sunanda Mahajan Uday Khopkar |
| author_facet | Bhushan Madke Vidya Kharkar Siddhi Chikhalkar Sunanda Mahajan Uday Khopkar |
| author_sort | Bhushan Madke |
| collection | DOAJ |
| description | We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy. |
| first_indexed | 2024-12-23T14:40:06Z |
| format | Article |
| id | doaj.art-2cbf2347f80449a0b3e2c6b9f153a2c0 |
| institution | Directory Open Access Journal |
| issn | 0019-5154 1998-3611 |
| language | English |
| last_indexed | 2024-12-23T14:40:06Z |
| publishDate | 2011-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Dermatology |
| spelling | doaj.art-2cbf2347f80449a0b3e2c6b9f153a2c02022-12-21T17:43:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Dermatology0019-51541998-36112011-01-0156558759010.4103/0019-5154.87165Successful treatment of multifocal cutaneous leishmaniasis with miltefosineBhushan MadkeVidya KharkarSiddhi ChikhalkarSunanda MahajanUday KhopkarWe report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy.http://www.e-ijd.org/article.asp?issn=0019-5154;year=2011;volume=56;issue=5;spage=587;epage=590;aulast=MadkeLeishmaniasismiltefosinemultifocal |
| spellingShingle | Bhushan Madke Vidya Kharkar Siddhi Chikhalkar Sunanda Mahajan Uday Khopkar Successful treatment of multifocal cutaneous leishmaniasis with miltefosine Indian Journal of Dermatology Leishmaniasis miltefosine multifocal |
| title | Successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
| title_full | Successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
| title_fullStr | Successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
| title_full_unstemmed | Successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
| title_short | Successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
| title_sort | successful treatment of multifocal cutaneous leishmaniasis with miltefosine |
| topic | Leishmaniasis miltefosine multifocal |
| url | http://www.e-ijd.org/article.asp?issn=0019-5154;year=2011;volume=56;issue=5;spage=587;epage=590;aulast=Madke |
| work_keys_str_mv | AT bhushanmadke successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT vidyakharkar successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT siddhichikhalkar successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT sunandamahajan successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine AT udaykhopkar successfultreatmentofmultifocalcutaneousleishmaniasiswithmiltefosine |