Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk
Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis. This study seeks to describe and compare the sociodemographic, clinical, and functional characteristics of At-Risk Mental State (ARMS) for psy...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-07-01
|
| Series: | Frontiers in Psychology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.911030/full |
| _version_ | 1818536848778067968 |
|---|---|
| author | Lourdes Nieto Tecelli Domínguez-Martínez Mauricio Rosel-Vales Ricardo Saracco-Alvarez Cesar Celada-Borja María Luisa Rascón-Gasca |
| author_facet | Lourdes Nieto Tecelli Domínguez-Martínez Mauricio Rosel-Vales Ricardo Saracco-Alvarez Cesar Celada-Borja María Luisa Rascón-Gasca |
| author_sort | Lourdes Nieto |
| collection | DOAJ |
| description | Few studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis. This study seeks to describe and compare the sociodemographic, clinical, and functional characteristics of At-Risk Mental State (ARMS) for psychosis youth and those with a first- or second-degree relative with psychosis (Familial High-Risk: FHR) in a Mexican sample. Twenty-one ARMS individuals and 21 with FHR were evaluated for sociodemographic characteristics, psychopathological symptoms, and functional impairment. ARMS individuals were significantly younger, had fewer years of schooling, and were more likely to be male than those in the FHR group. Groups did not differ as regards marital status or occupation. The ARMS group showed greater severity of prodromal symptoms, schizotypal personality traits, and general psychopathology than the FHR group. In addition, they reported more premorbid adjustment deficit from early adolescence than the FHR group. Current overall social and role functioning was significantly lower in the ARMS group. Findings are consistent with ARMS studies from other countries. First- or second-degree relatives of patients with psychosis should be considered a vulnerable group as they display several symptoms of general psychopathology and may experience social adjustment problems in their adult lives. The lack of early detection and intervention psychosis programs in Mexico underlines the need to prioritize the development of preventive strategies to help close the care gap. |
| first_indexed | 2024-12-11T18:43:13Z |
| format | Article |
| id | doaj.art-2cc0d3df52804015b1cc5d6e07d385d9 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-11T18:43:13Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-2cc0d3df52804015b1cc5d6e07d385d92022-12-22T00:54:32ZengFrontiers Media S.A.Frontiers in Psychology1664-10782022-07-011310.3389/fpsyg.2022.911030911030Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High RiskLourdes Nieto0Tecelli Domínguez-Martínez1Mauricio Rosel-Vales2Ricardo Saracco-Alvarez3Cesar Celada-Borja4María Luisa Rascón-Gasca5Division of Epidemiological and Psychosocial Research, Center for Global Mental Health Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, MexicoDivision of Epidemiological and Psychosocial Research, Center for Global Mental Health Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, MexicoSchizophrenia Clinic, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, MexicoDepartment of Clinical Research, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, MexicoSchizophrenia Clinic, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, MexicoDivision of Epidemiological and Psychosocial Research, Department of Social Sciences in Health, National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, MexicoFew studies have explored the differences in clinical psychopathology between youth at high risk for psychosis and those at familial high risk for psychosis. This study seeks to describe and compare the sociodemographic, clinical, and functional characteristics of At-Risk Mental State (ARMS) for psychosis youth and those with a first- or second-degree relative with psychosis (Familial High-Risk: FHR) in a Mexican sample. Twenty-one ARMS individuals and 21 with FHR were evaluated for sociodemographic characteristics, psychopathological symptoms, and functional impairment. ARMS individuals were significantly younger, had fewer years of schooling, and were more likely to be male than those in the FHR group. Groups did not differ as regards marital status or occupation. The ARMS group showed greater severity of prodromal symptoms, schizotypal personality traits, and general psychopathology than the FHR group. In addition, they reported more premorbid adjustment deficit from early adolescence than the FHR group. Current overall social and role functioning was significantly lower in the ARMS group. Findings are consistent with ARMS studies from other countries. First- or second-degree relatives of patients with psychosis should be considered a vulnerable group as they display several symptoms of general psychopathology and may experience social adjustment problems in their adult lives. The lack of early detection and intervention psychosis programs in Mexico underlines the need to prioritize the development of preventive strategies to help close the care gap.https://www.frontiersin.org/articles/10.3389/fpsyg.2022.911030/fullclinical high risk for psychosisat-risk mental statesfamily riskunaffected relativesearly psychosis |
| spellingShingle | Lourdes Nieto Tecelli Domínguez-Martínez Mauricio Rosel-Vales Ricardo Saracco-Alvarez Cesar Celada-Borja María Luisa Rascón-Gasca Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk Frontiers in Psychology clinical high risk for psychosis at-risk mental states family risk unaffected relatives early psychosis |
| title | Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk |
| title_full | Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk |
| title_fullStr | Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk |
| title_full_unstemmed | Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk |
| title_short | Clinical and Functional Differences Between Mexican Youth at Clinical High Risk for Psychosis and With Familial High Risk |
| title_sort | clinical and functional differences between mexican youth at clinical high risk for psychosis and with familial high risk |
| topic | clinical high risk for psychosis at-risk mental states family risk unaffected relatives early psychosis |
| url | https://www.frontiersin.org/articles/10.3389/fpsyg.2022.911030/full |
| work_keys_str_mv | AT lourdesnieto clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk AT tecellidominguezmartinez clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk AT mauricioroselvales clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk AT ricardosaraccoalvarez clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk AT cesarceladaborja clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk AT marialuisarascongasca clinicalandfunctionaldifferencesbetweenmexicanyouthatclinicalhighriskforpsychosisandwithfamilialhighrisk |