Toxoplasma gondii Infection Induces High Mobility Group Box 1 Released from Mouse Macrophages

Toxoplasma gondii Infection Induces High Mobility Group Box 1 Released from Mouse Macrophages

High mobility group box 1 (HMGB1) is abundantly expressed in intracellular engaged DNA binding ability. However, more importantly, it is a weapon against infection through proinflammatory response and immune regulation while released to extracellular. Toxoplasma gondii causes inflammatory pathologic...

Full description

Bibliographic Details
Main Authors: Qun Liu, Hui Wang, Muzi Li, Jing Liu, Jianhai Xu, Qian Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Microbiology
Subjects:
Toxoplasma gondii
HMGB1
IFN-γ
proinflammatory response
caspase-1
inflammasome
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00658/full

Similar Items

Similar Items