Children gut microbiota exhibits a different composition and metabolic profile after in vitro exposure to Clostridioides difficile and increases its sporulation

Children gut microbiota exhibits a different composition and metabolic profile after in vitro exposure to Clostridioides difficile and increases its sporulation

Clostridioides difficile (Clostridium difficile) infection (CDI) is one of the main public health concerns in adults, while children under 2 years of age are often colonized asymptomatically. In both adults and children, CDI is strongly associated with disturbances in gut microbiota. In this study,...

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Bibliographic Details
Main Authors: Sabina Horvat, Aleksander Mahnic, Damjan Makuc, Klemen Pečnik, Janez Plavec, Maja Rupnik
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
Clostridioides difficile
gut microbiota
sporulation
metabolomic
children
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1042526/full

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