Effect of HIV‐1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction

Effect of HIV‐1 Infection on Angiopoietin 1 and 2 Levels and Measures of Microvascular and Macrovascular Endothelial Dysfunction

Background Individuals infected with HIV have an increased risk of developing cardiovascular disease; yet, the underlying mechanisms remain unknown. Recent evidence has implicated the Tie‐2 tyrosine kinase receptor system and its associated ligands ANG1 (angiopoietin 1) and ANG2 (angiopoietin 2) in...

Descripció completa

Dades bibliogràfiques
Autors principals:	Anjali B. Thakkar, Yifei Ma, Mark Dela Cruz, Yuaner Wu, Victor Arechiga, Shreya Swaminathan, Peter Ganz, Alan H. B. Wu, Rebecca Scherzer, Steven Deeks, Priscilla Y. Hsue
Format:	Article
Idioma:	English
Publicat:	Wiley 2021-11-01
Col·lecció:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Matèries:	angiopoietin 1 angiopoietin 2 endothelial dysfunction endothelial homeostasis HIV
Accés en línia:	https://www.ahajournals.org/doi/10.1161/JAHA.121.021397

Ítems similars

Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro Angiogenesis
per: Sharon Harel, et al.
Publicat: (2020-07-01)

The Angiopoietin/Tie2 Pathway in Hepatocellular Carcinoma
per: Bart Vanderborght, et al.
Publicat: (2020-10-01)

Angiopoietins as Predictor Indexes in COVID-19 Patients in Delta and Omicron Waves
per: Panagiota Tsiatsiou, et al.
Publicat: (2024-04-01)

Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8
per: Kelli L. Sylvers-Davie, et al.
Publicat: (2021-01-01)

Insight into the Role of Angiopoietins in Ageing-Associated Diseases
per: Shin-ichiro Hayashi, et al.
Publicat: (2020-12-01)

Stimulated mast cells promote maturation of myocardial microvascular endothelial cell neovessels by modulating the angiopoietin-Tie-2 signaling pathway
per: Z.H. Wang, et al.
Publicat: (2013-11-01)

Assessment of peripheral blood concentration of angiopoietin 1, angiopoietin 2 and Tie-2 (a tyrosine kinase receptor) of patients with goitre treated surgically
per: Joanna Kalupa, et al.
Publicat: (2011-06-01)

Molecular regulation and role of angiogenesis in reproduction
per: Momchil Rizov, et al.
Publicat: (2017-04-01)

Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage
per: Hua Gu, et al.
Publicat: (2016-12-01)

ETS1, ELK1, and ETV4 Transcription Factors Regulate Angiopoietin-1 Signaling and the Angiogenic Response in Endothelial Cells
per: Sharon Harel, et al.
Publicat: (2021-07-01)

Angiopoietin-2 Inhibition of Thrombomodulin-Mediated Anticoagulation—A Novel Mechanism That May Contribute to Hypercoagulation in Critically Ill COVID-19 Patients
per: Michael Hultström, et al.
Publicat: (2022-06-01)

Endothelial Permeability and the Angiopoietin/Tie2 System Following Mild and Severe COVID-19
per: Carolien Volleman, et al.
Publicat: (2023-07-01)

Serum levels of angiopoietin-2 and vascular endothelial growth factor in severe refractory asthma
per: Mohamed Hantera, et al.
Publicat: (2014-10-01)

miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and Differentiation
per: Veronica Sanchez, et al.
Publicat: (2025-01-01)

Angiopoietin-2 outperforms other endothelial biomarkers associated with severe acute kidney injury in patients with severe sepsis and respiratory failure
per: Wen-Kuang Yu, et al.
Publicat: (2021-02-01)

Rap1 Is Involved in Angiopoietin-1-Induced Cell-Cell Junction Stabilization and Endothelial Cell Sprouting
per: Vanda Gaonac’h-Lovejoy, et al.
Publicat: (2020-01-01)

Angiopoietin-2 is associated with metabolic syndrome in chronic kidney disease
per: Fan-Chi Chang, et al.
Publicat: (2021-12-01)

Distinct Clinical Impact and Biological Function of Angiopoietin and Angiopoietin-like Proteins in Human Breast Cancer
per: Hui Yang, et al.
Publicat: (2021-09-01)

Serum Angiopoietin-1/Angiopoietin-2 at 16-18 Weeks of Gestation to Predict Preeclampsia
per: Vorapong Phupong, et al.
Publicat: (2021-07-01)

Prognostic significance of the angiopoietin-2 for early prediction of septic shock in severe sepsis patients
per: Luu Thi Thanh Duyen, et al.
Publicat: (2022-12-01)

Serum angiopoietin-2/angiopoietin-1 ratio is associated with cardiovascular and all-cause mortality in peritoneal dialysis patients: a prospective cohort study
per: Han Li, et al.
Publicat: (2024-12-01)

Serum angiopoietin-1 concentration does not distinguish patients with ischaemic stroke from those presenting to hospital with ischaemic stroke mimics
per: Joseph V. Moxon, et al.
Publicat: (2022-11-01)

Therapeutic Effect of Alprostadil in Diabetic Nephropathy: Possible Roles of Angiopoietin-2 and IL-18
per: Changqing Luo, et al.
Publicat: (2014-08-01)

Biomarkers of endothelial dysfunction predict sepsis mortality in young infants: a matched case-control study
per: Julie Korol Wright, et al.
Publicat: (2018-03-01)

Role of Angiopoietins and Tie-2 in Diabetic Retinopathy
per: Nervana Khalaf, et al.
Publicat: (2017-08-01)

Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology
per: Racheal G. Akwii, et al.
Publicat: (2019-05-01)

Deregulation of angiopoietin-like 4 slows ovarian cancer progression through vascular endothelial growth factor receptor 2 phosphorylation
per: Yuxian Wu, et al.
Publicat: (2021-03-01)

Serum Angiopoietin-1 and -2 and VEGF are associated with severe disease in vivax malaria
per: Srinivas H Gowda, et al.
Publicat: (2020-01-01)

Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity
per: Yan Q. Chen, et al.
Publicat: (2021-09-01)

Preclinical validation of a novel metastasis‐inhibiting Tie1 function‐blocking antibody
per: Mahak Singhal, et al.
Publicat: (2020-04-01)

Decreased circulating levels of angiopoietin – 1 (Ang-1) are associated with the presence of multinodular goiter or differentiated thyroid cancer
per: Alexander M. Nixon, et al.
Publicat: (2023-06-01)

Association of Ang/Tie2 pathway mediators with endothelial barrier integrity and disease severity in COVID-19
per: Carla Roberta Peachazepi Moraes, et al.
Publicat: (2023-02-01)

Impact of Angiopoietin-2 on Kidney Diseases
per: Mei Li, et al.
Publicat: (2023-03-01)

Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue
per: Win Khaing, et al.
Publicat: (2025-02-01)

Reduced Angiopoietin Factor 2 Levels Are Correlated with Better Cardiac Function and Prognosis in Valvular Heart Disease
per: Jian Hou, et al.
Publicat: (2022-06-01)

Angiopoietin-2 as a biomarker of non-ST-segment elevation myocardial infarction in patients with or without type 2 diabetes
per: Tomasz Skowerski, et al.
Publicat: (2019-11-01)

Prognostic value of endothelial biomarkers in refractory cardiogenic shock with ECLS: a prospective monocentric study
per: Tsung-Yu Tsai, et al.
Publicat: (2019-05-01)

On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity
per: Oleg Kovrov, et al.
Publicat: (2019-04-01)

Endothelin-1/Endothelin Receptor Type A-Angiopoietins/Tie-2 Pathway in Regulating the Cross Talk Between Glomerular Endothelial Cells and Podocytes in Trichloroethylene-Induced Renal Immune Injury
per: Xie H, et al.
Publicat: (2021-03-01)

Role of Angiopoietins in Development of Cancer and Neoplasia Associated with Viral Infection
per: Xiaolan Yu, et al.
Publicat: (2020-02-01)