Hydrophilic nanofibers with aligned topography modulate macrophage-mediated host responses via the NLRP3 inflammasome

Hydrophilic nanofibers with aligned topography modulate macrophage-mediated host responses via the NLRP3 inflammasome

Abstract Successful biomaterial implantation requires appropriate immune responses. Macrophages are key mediators involved in this process. Currently, exploitation of the intrinsic properties of biomaterials to modulate macrophages and immune responses is appealing. In this study, we prepared hydrop...

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Bibliographic Details
Main Authors: Yiming Ren, Yi Chen, Wei Chen, Haotian Deng, Peiqi Li, Yubo Liu, Cangjian Gao, Guangzhao Tian, Chao Ning, Zhiguo Yuan, Xiang Sui, Shuyun Liu, Quanyi Guo
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Nanobiotechnology
Subjects:
Topography
Hydrophilicity
Macrophage
NLRP3 inflammasome
Immunomodulation
Peritendinous adhesion
Online Access:https://doi.org/10.1186/s12951-023-02024-9

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