Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy
Abstract Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indicating that this drug may not be active against MM...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-09-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.3019 |
| _version_ | 1818485511600209920 |
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| author | Ayad M. Al‐Katib Hussein Gaith Dahlia Sano Sayf Al‐Katib Michelle Bonnett Zyad Kafri |
| author_facet | Ayad M. Al‐Katib Hussein Gaith Dahlia Sano Sayf Al‐Katib Michelle Bonnett Zyad Kafri |
| author_sort | Ayad M. Al‐Katib |
| collection | DOAJ |
| description | Abstract Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indicating that this drug may not be active against MM. |
| first_indexed | 2024-12-10T16:10:23Z |
| format | Article |
| id | doaj.art-2cd589ba77954aa3940bc8329b6b53b1 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-12-10T16:10:23Z |
| publishDate | 2020-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-2cd589ba77954aa3940bc8329b6b53b12022-12-22T01:42:08ZengWileyClinical Case Reports2050-09042020-09-01891797180110.1002/ccr3.3019Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapyAyad M. Al‐Katib0Hussein Gaith1Dahlia Sano2Sayf Al‐Katib3Michelle Bonnett4Zyad Kafri5Lymphoma Research Laboratory Department of Internal Medicine Wayne State University School of Medicine (WSU SOM) Detroit MI USALymphoma Research Laboratory Department of Internal Medicine Wayne State University School of Medicine (WSU SOM) Detroit MI USADepartment of Oncology Karmanos Cancer Institute WSU SOM Detroit MI USADepartment of Diagnostic Radiology and Molecular Imaging Beaumont Health Oakland University William Beaumont School of Medicine Royal Oak MI USADepartment of Pathology Ascension St. John Hospital and Medical Center Detroit MI USAVan Elslander Cancer Center Grosse Pointe Woods MI USAAbstract Ibrutinib is approved for chronic lymphocytic leukemia (CLL). However, its role in the treatment of multiple myeloma (MM) is not clear and is under investigation. We report a case of CLL that developed MM while on therapy with ibrutinib indicating that this drug may not be active against MM.https://doi.org/10.1002/ccr3.3019bruton tyrosine kinase inhibitorschronic lymphocytic leukemiaibrutinibmultiple myeloma |
| spellingShingle | Ayad M. Al‐Katib Hussein Gaith Dahlia Sano Sayf Al‐Katib Michelle Bonnett Zyad Kafri Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy Clinical Case Reports bruton tyrosine kinase inhibitors chronic lymphocytic leukemia ibrutinib multiple myeloma |
| title | Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy |
| title_full | Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy |
| title_fullStr | Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy |
| title_full_unstemmed | Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy |
| title_short | Emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy |
| title_sort | emergence of overt myeloma in a patient with chronic lymphocytic leukemia on ibrutinib therapy |
| topic | bruton tyrosine kinase inhibitors chronic lymphocytic leukemia ibrutinib multiple myeloma |
| url | https://doi.org/10.1002/ccr3.3019 |
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