High generation of reactive oxygen species from neutrophils in patients with severe COVID-19

High generation of reactive oxygen species from neutrophils in patients with severe COVID-19

Abstract Neutrophilia and an elevated neutrophil:lymphocyte ratio are both characteristic features of severe COVID-19 infection. However, functional neutrophil responses have been poorly investigated in this setting. We utilised a novel PMA-based stimulation assay to determine neutrophil-derived rea...

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Bibliographic Details
Main Authors:	Tonny Veenith, Helena Martin, Martin Le Breuilly, Tony Whitehouse, Fang Gao-Smith, Niharika Duggal, Janet M. Lord, Rubina Mian, David Sarphie, Paul Moss
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-13825-7

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