Active unicameral bone cysts: control firstly, cure secondly
Abstract Purpose This retrospective study evaluated the efficacy of minimally invasive surgery to control cyst progression for active unicameral bone cysts (AUBC) by intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting. Methods From May 2010 to May 20...
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| Format: | Article |
| Language: | English |
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BMC
2019-08-01
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| Series: | Journal of Orthopaedic Surgery and Research |
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| Online Access: | http://link.springer.com/article/10.1186/s13018-019-1326-3 |
| _version_ | 1797999382216310784 |
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| author | Qing Liu Hongbo He Hao Zeng Yuhao Yuan Zhiwei Wang Xiaopeng Tong Wei Luo |
| author_facet | Qing Liu Hongbo He Hao Zeng Yuhao Yuan Zhiwei Wang Xiaopeng Tong Wei Luo |
| author_sort | Qing Liu |
| collection | DOAJ |
| description | Abstract Purpose This retrospective study evaluated the efficacy of minimally invasive surgery to control cyst progression for active unicameral bone cysts (AUBC) by intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting. Methods From May 2010 to May 2017, patients diagnosed with AUBC who underwent percutaneous double-needle intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting were retrospectively reviewed. Recurrence was defined by modified Neer scale score. Patients were followed up regularly, and previous imaging findings were compared to evaluate treatment efficacy. Results The 26 patients (17 boys, 9 girls, mean age, 9.4 ± 3.1 years) were followed up for a mean 45.1 months (range, 24–82 months). Follow-up consisted of clinical evaluation and radiographic review. Twenty patients (77%) achieved latent disease stage after the first treatment, while six (23%) achieved it after the second treatment. Postoperative pathological fracture imaging scores were score I in 18 (70%), score II in five (19%), score III in two (8%), and score IV in one patient (4%). All 26 patients returned to their full activities and were asymptomatic at the most recent follow-up. The success rate (scores I and II) independent of the number of treatments was 89%. Treatment time was correlated with cyst size and length. Sex, age, cyst location and size, pathological fracture, and other clinical factors or radiological data did not influence the curative effect. No other complications occurred. Conclusions For AUBC, minimally invasive treatment is feasible to control cyst progression and then cure it without sequelae. Intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting are an excellent choice. |
| first_indexed | 2024-04-11T11:03:52Z |
| format | Article |
| id | doaj.art-2cdc2f104ab348439a725d9458b543cd |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-11T11:03:52Z |
| publishDate | 2019-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-2cdc2f104ab348439a725d9458b543cd2022-12-22T04:28:26ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2019-08-011411910.1186/s13018-019-1326-3Active unicameral bone cysts: control firstly, cure secondlyQing Liu0Hongbo He1Hao Zeng2Yuhao Yuan3Zhiwei Wang4Xiaopeng Tong5Wei Luo6Department of Orthopaedics, Xiangya Hospital, Central South UniversityDepartment of Orthopaedics, Xiangya Hospital, Central South UniversityDepartment of Orthopaedics, Xiangya Hospital, Central South UniversityDepartment of Orthopaedics, Xiangya Hospital, Central South UniversityDepartment of Orthopaedics, Xiangya Hospital, Central South UniversityDepartment of Orthopaedics, Xiangya Hospital, Central South UniversityDepartment of Orthopaedics, Xiangya Hospital, Central South UniversityAbstract Purpose This retrospective study evaluated the efficacy of minimally invasive surgery to control cyst progression for active unicameral bone cysts (AUBC) by intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting. Methods From May 2010 to May 2017, patients diagnosed with AUBC who underwent percutaneous double-needle intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting were retrospectively reviewed. Recurrence was defined by modified Neer scale score. Patients were followed up regularly, and previous imaging findings were compared to evaluate treatment efficacy. Results The 26 patients (17 boys, 9 girls, mean age, 9.4 ± 3.1 years) were followed up for a mean 45.1 months (range, 24–82 months). Follow-up consisted of clinical evaluation and radiographic review. Twenty patients (77%) achieved latent disease stage after the first treatment, while six (23%) achieved it after the second treatment. Postoperative pathological fracture imaging scores were score I in 18 (70%), score II in five (19%), score III in two (8%), and score IV in one patient (4%). All 26 patients returned to their full activities and were asymptomatic at the most recent follow-up. The success rate (scores I and II) independent of the number of treatments was 89%. Treatment time was correlated with cyst size and length. Sex, age, cyst location and size, pathological fracture, and other clinical factors or radiological data did not influence the curative effect. No other complications occurred. Conclusions For AUBC, minimally invasive treatment is feasible to control cyst progression and then cure it without sequelae. Intracystic methylprednisolone injection, percutaneous curettage, and autogenous bone marrow grafting are an excellent choice.http://link.springer.com/article/10.1186/s13018-019-1326-3Unicameral bone cystsPercutaneous curettageAutogenous bone marrow graftingIntracystic methylprednisolone injection |
| spellingShingle | Qing Liu Hongbo He Hao Zeng Yuhao Yuan Zhiwei Wang Xiaopeng Tong Wei Luo Active unicameral bone cysts: control firstly, cure secondly Journal of Orthopaedic Surgery and Research Unicameral bone cysts Percutaneous curettage Autogenous bone marrow grafting Intracystic methylprednisolone injection |
| title | Active unicameral bone cysts: control firstly, cure secondly |
| title_full | Active unicameral bone cysts: control firstly, cure secondly |
| title_fullStr | Active unicameral bone cysts: control firstly, cure secondly |
| title_full_unstemmed | Active unicameral bone cysts: control firstly, cure secondly |
| title_short | Active unicameral bone cysts: control firstly, cure secondly |
| title_sort | active unicameral bone cysts control firstly cure secondly |
| topic | Unicameral bone cysts Percutaneous curettage Autogenous bone marrow grafting Intracystic methylprednisolone injection |
| url | http://link.springer.com/article/10.1186/s13018-019-1326-3 |
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