Cryoballoon ablation guided by a novel wide-band dielectric imaging system
Background and aimTo investigate the feasibility, acute efficacy, periprocedural safety, and procedural parameters of CB-based PVI guided by KODEX-EPD using different occlusion tool software versions.Methods and resultsA total of 173 patients (60/173 (35%) paroxysmal AF, 64 ± 12 years, 66/173 (38%)...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.967341/full |
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| author | Laura Rottner Julius Obergassel Ilaria My Paulus Kirchhof Paulus Kirchhof Feifan Ouyang Bruno Reissmann Andreas Metzner Andreas Rillig |
| author_facet | Laura Rottner Julius Obergassel Ilaria My Paulus Kirchhof Paulus Kirchhof Feifan Ouyang Bruno Reissmann Andreas Metzner Andreas Rillig |
| author_sort | Laura Rottner |
| collection | DOAJ |
| description | Background and aimTo investigate the feasibility, acute efficacy, periprocedural safety, and procedural parameters of CB-based PVI guided by KODEX-EPD using different occlusion tool software versions.Methods and resultsA total of 173 patients (60/173 (35%) paroxysmal AF, 64 ± 12 years, 66/173 (38%) female), underwent CB-based PVI guided by KODEX-EPD between August 2019 and October 2021. Acute PVI was achieved in all the patients. Total fluoroscopy time and dye volume were 13.9 [10.6–19.4] min and 47.5 [20–70] ml. Periprocedural complications occurred in 3 (2%) of the 173 patients. As part of the continued development program, different software versions were used, including 1.4.6 on 38 (22%), 1.4.6a on 33 (19%), 1.4.7 on 41 (24%), and 1.4.8 on 61 (35%) of the patients. Outcomes were compared between software versions by a univariate analysis. Sensitivity analyses were performed to account for confounders. Median fluoroscopy time was decreased by 6.4 min (37.3%), and the median volume of dye was decreased by 32.5 ml (52%) from versions 1.4.6 to 1.4.8. Software version was a significant predictor of fluoroscopy time and dye volume, while reductions in procedure duration and dose area product were observed but mainly explained via confounders.ConclusionCB-based PVI guided by KODEX-EPD is feasible and safe. Progressive software improvements appear to be associated with lower fluoroscopy duration and dye use. Further studies are needed to evaluate the advantage of KODEX-EPD-guided compared to conventional CB-PVI. |
| first_indexed | 2024-04-13T19:05:34Z |
| format | Article |
| id | doaj.art-2cdd39fe6a2b4b05823c909a98f245f0 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-13T19:05:34Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-2cdd39fe6a2b4b05823c909a98f245f02022-12-22T02:33:58ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-08-01910.3389/fcvm.2022.967341967341Cryoballoon ablation guided by a novel wide-band dielectric imaging systemLaura Rottner0Julius Obergassel1Ilaria My2Paulus Kirchhof3Paulus Kirchhof4Feifan Ouyang5Bruno Reissmann6Andreas Metzner7Andreas Rillig8Department of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, United KingdomDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyDepartment of Cardiology, University Heart and Vascular Center Hamburg, Hamburg, GermanyBackground and aimTo investigate the feasibility, acute efficacy, periprocedural safety, and procedural parameters of CB-based PVI guided by KODEX-EPD using different occlusion tool software versions.Methods and resultsA total of 173 patients (60/173 (35%) paroxysmal AF, 64 ± 12 years, 66/173 (38%) female), underwent CB-based PVI guided by KODEX-EPD between August 2019 and October 2021. Acute PVI was achieved in all the patients. Total fluoroscopy time and dye volume were 13.9 [10.6–19.4] min and 47.5 [20–70] ml. Periprocedural complications occurred in 3 (2%) of the 173 patients. As part of the continued development program, different software versions were used, including 1.4.6 on 38 (22%), 1.4.6a on 33 (19%), 1.4.7 on 41 (24%), and 1.4.8 on 61 (35%) of the patients. Outcomes were compared between software versions by a univariate analysis. Sensitivity analyses were performed to account for confounders. Median fluoroscopy time was decreased by 6.4 min (37.3%), and the median volume of dye was decreased by 32.5 ml (52%) from versions 1.4.6 to 1.4.8. Software version was a significant predictor of fluoroscopy time and dye volume, while reductions in procedure duration and dose area product were observed but mainly explained via confounders.ConclusionCB-based PVI guided by KODEX-EPD is feasible and safe. Progressive software improvements appear to be associated with lower fluoroscopy duration and dye use. Further studies are needed to evaluate the advantage of KODEX-EPD-guided compared to conventional CB-PVI.https://www.frontiersin.org/articles/10.3389/fcvm.2022.967341/fullcryoballoon ablationocclusion tool softwaredielectric imaging systempulmonary vein ablation/isolationhigh resolution imaging |
| spellingShingle | Laura Rottner Julius Obergassel Ilaria My Paulus Kirchhof Paulus Kirchhof Feifan Ouyang Bruno Reissmann Andreas Metzner Andreas Rillig Cryoballoon ablation guided by a novel wide-band dielectric imaging system Frontiers in Cardiovascular Medicine cryoballoon ablation occlusion tool software dielectric imaging system pulmonary vein ablation/isolation high resolution imaging |
| title | Cryoballoon ablation guided by a novel wide-band dielectric imaging system |
| title_full | Cryoballoon ablation guided by a novel wide-band dielectric imaging system |
| title_fullStr | Cryoballoon ablation guided by a novel wide-band dielectric imaging system |
| title_full_unstemmed | Cryoballoon ablation guided by a novel wide-band dielectric imaging system |
| title_short | Cryoballoon ablation guided by a novel wide-band dielectric imaging system |
| title_sort | cryoballoon ablation guided by a novel wide band dielectric imaging system |
| topic | cryoballoon ablation occlusion tool software dielectric imaging system pulmonary vein ablation/isolation high resolution imaging |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.967341/full |
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