Variants in the interleukin 8 gene and the response to inhaled bronchodilators in cystic fibrosis

Variants in the interleukin 8 gene and the response to inhaled bronchodilators in cystic fibrosis

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Objective: Interleukin 8 protein promotes inflammatory responses, even in airways. The presence of interleukin 8 gene variants causes altered inflammatory responses and possibly varied responses to inhaled bronchodilators. Thus, this study analyzed the interleukin 8 variants (rs4073, rs2227306, and...

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Bibliographic Details
Main Authors: Larissa Lazzarini Furlan, José Dirceu Ribeiro, Carmen Sílvia Bertuzzo, João Batista Salomão Junior, Dorotéia Rossi Silva Souza, Fernando Augusto Lima Marson
Format: Article
Language:Portuguese
Published: Brazilian Society of Pediatrics 2017-11-01
Series:Jornal de Pediatria (Versão em Português)
Subjects:
CFTR
Disease severity
Interleukin 8
Lung function
Online Access:http://www.sciencedirect.com/science/article/pii/S2255553617300794
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