p63α and γ Induce TAU Phosphorylation in Cultured Mammalian Cells

p63α and γ Induce TAU Phosphorylation in Cultured Mammalian Cells

Here we show by western blotting that transcriptionally active isoforms of p63 (p63α and p63γ) induce the phosphorylation of human 2N4R tau at the tau-1/AT8 epitope in HEK293a cells; a phospho-epitope increased in Alzheimer's disease. Confocal microscopy shows that tau and p63α are spatially se...

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Bibliographic Details
Main Authors:	Claudie Hooper, Reem Soliman, Simon Lovestone, Richard Killick
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-01-01
Series:	Journal of Experimental Neuroscience
Online Access:	https://doi.org/10.4137/JEN.S6295

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