Treatment of painful diabetic neuropathy
Painful diabetic neuropathy is observed in almost half of patients with diabetes mellitus (DM) and is associated with a decrease in the quality of life, emotional disorders, sleep disorders. The achievement and maintenance of the normal level of glucose in the blood is the basis for the prevention a...
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ZAO "Consilium Medicum"
2021-11-01
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Series: | Consilium Medicum |
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Online Access: | https://consilium.orscience.ru/2075-1753/article/viewFile/96615/70888 |
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author | Vladimir A. Parfenov Mariya V. Konyashova |
author_facet | Vladimir A. Parfenov Mariya V. Konyashova |
author_sort | Vladimir A. Parfenov |
collection | DOAJ |
description | Painful diabetic neuropathy is observed in almost half of patients with diabetes mellitus (DM) and is associated with a decrease in the quality of life, emotional disorders, sleep disorders. The achievement and maintenance of the normal level of glucose in the blood is the basis for the prevention and treatment of DM, but this often does not allow the patient from pain and other clinical manifestations of neuropathy. Drug diabetic neuropathy therapy methods are discussed, the results of randomized placebo controlled studies on the efficiency and side effects of various drugs are analyzed. It is noted that pregabalin and gabapenitin, as antidepressants duloxetin, venlafaxin and amitriptyline, are most effective as anti-epileptic agents. In our country, with painful diabetic neuropathy, the preparations of a-lipoic acid are widely used. Analyzed data on efficacy and complications of the use of transcutaneus electrical nerves stimulation and spinal cord stimulation with pain diabetic neuropathy refractory to drug therapy. It is noted that many patients with pain diabetic neuropathy have combined diseases, detection and effective treatment of which can lead to an improvement in the state of patients and reduce the manifestations of neuropathy. |
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format | Article |
id | doaj.art-2ce61be29ed641fe86cfd0c746f625be |
institution | Directory Open Access Journal |
issn | 2075-1753 2542-2170 |
language | Russian |
last_indexed | 2024-12-13T01:24:18Z |
publishDate | 2021-11-01 |
publisher | ZAO "Consilium Medicum" |
record_format | Article |
series | Consilium Medicum |
spelling | doaj.art-2ce61be29ed641fe86cfd0c746f625be2022-12-22T00:04:09ZrusZAO "Consilium Medicum"Consilium Medicum2075-17532542-21702021-11-01231184184610.26442/20751753.2021.11.2012304323Treatment of painful diabetic neuropathyVladimir A. Parfenov0https://orcid.org/0000-0002-1992-7960Mariya V. Konyashova1https://orcid.org/0000-0002-3667-7959Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Painful diabetic neuropathy is observed in almost half of patients with diabetes mellitus (DM) and is associated with a decrease in the quality of life, emotional disorders, sleep disorders. The achievement and maintenance of the normal level of glucose in the blood is the basis for the prevention and treatment of DM, but this often does not allow the patient from pain and other clinical manifestations of neuropathy. Drug diabetic neuropathy therapy methods are discussed, the results of randomized placebo controlled studies on the efficiency and side effects of various drugs are analyzed. It is noted that pregabalin and gabapenitin, as antidepressants duloxetin, venlafaxin and amitriptyline, are most effective as anti-epileptic agents. In our country, with painful diabetic neuropathy, the preparations of a-lipoic acid are widely used. Analyzed data on efficacy and complications of the use of transcutaneus electrical nerves stimulation and spinal cord stimulation with pain diabetic neuropathy refractory to drug therapy. It is noted that many patients with pain diabetic neuropathy have combined diseases, detection and effective treatment of which can lead to an improvement in the state of patients and reduce the manifestations of neuropathy.https://consilium.orscience.ru/2075-1753/article/viewFile/96615/70888painful diabetic neuropathypregabalingabapentineneurotineduloxetinevenlafaxinecapsacina-lipoic acid preparationsthioctacidpercutaneous electrical stimulation of nervesspinal cord stimulation |
spellingShingle | Vladimir A. Parfenov Mariya V. Konyashova Treatment of painful diabetic neuropathy Consilium Medicum painful diabetic neuropathy pregabalin gabapentine neurotine duloxetine venlafaxine capsacin a-lipoic acid preparations thioctacid percutaneous electrical stimulation of nerves spinal cord stimulation |
title | Treatment of painful diabetic neuropathy |
title_full | Treatment of painful diabetic neuropathy |
title_fullStr | Treatment of painful diabetic neuropathy |
title_full_unstemmed | Treatment of painful diabetic neuropathy |
title_short | Treatment of painful diabetic neuropathy |
title_sort | treatment of painful diabetic neuropathy |
topic | painful diabetic neuropathy pregabalin gabapentine neurotine duloxetine venlafaxine capsacin a-lipoic acid preparations thioctacid percutaneous electrical stimulation of nerves spinal cord stimulation |
url | https://consilium.orscience.ru/2075-1753/article/viewFile/96615/70888 |
work_keys_str_mv | AT vladimiraparfenov treatmentofpainfuldiabeticneuropathy AT mariyavkonyashova treatmentofpainfuldiabeticneuropathy |